Articular cartilage biomechanics, mechanobiology, and tissue engineering

Eugene Koay, Kyriacos Athanasiou

Research output: Chapter in Book/Report/Conference proceedingChapter

3 Scopus citations


Tissue engineering is a promising solution to address articular cartilage pathology. The creation of strategies for functional replacement of diseased cartilage relies heavily on the knowledge of the physiology and development of articular cartilage, especially in terms of the influence of biomechanical forces on the tissue. This review will present the current knowledge of biomechanical structure-function relationships of native articular cartilage, and synthesize this knowledge with strategies to engineer the tissue in vitro.

Original languageEnglish (US)
Title of host publicationBiomechanical Systems Technology
Subtitle of host publicationMuscular Skeletal Systems
PublisherWorld Scientific Publishing Co.
Number of pages37
ISBN (Electronic)9789812771384
ISBN (Print)9812707980, 9789812709837
StatePublished - Jan 1 2009


  • Articular cartilage
  • Mechanobiology
  • Mechanotransduction
  • Tissue engineering

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)
  • Medicine(all)


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