Arteriographic demonstration of coronary artery spasm during thrombolysis

Amin H. Karim, W. Bennett, S. J. Silver, Neal Kleiman, D. Goodman, J. Heibig

Research output: Contribution to journalArticlepeer-review


A 60-year-old man with an acute inferior-wall myocardial infarction was noted, on arteriography, to have an occluded distal right coronary artery. The vessel was reopened with intravenous tissue plasminogen activator; during resolution of the clot, spasm was observed arteriographically but was successfully treated with intracoronary nitroglycerin. Follow-up arteriography showed a normal right coronary artery. The significance of this case lies in the fact that we were able to document the occurrence of spasm during coronary thrombolysis; such documentation supports the hypothesis that spasm may be a factor in the initiation of coronary thrombosis.

Original languageEnglish (US)
Pages (from-to)52-54
Number of pages3
JournalTexas Heart Institute Journal
Issue number1
StatePublished - Jan 1 1988

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine


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