@article{a402b38810c042d38ac6223042e39718,
title = "Application of whole-genome sequencing to an unusual outbreak of invasive group a streptococcal disease",
abstract = "Whole-genome analysis was applied to investigate atypical point-source transmission of 2 invasive group A streptococcal (GAS) infections. Isolates were serotype M4, ST39, and genetically indistinguishable. Comparison with MGAS10750 revealed nonsynonymous polymorphisms in ropB and increased speB transcription. This study demonstrates the usefulness of whole-genome analyses for GAS outbreaks.",
keywords = "Group A streptococcus, Invasive disease, Streptococcus pyogenes, Whole-genome sequencing, speB",
author = "Jessica Galloway-Pe{\~n}a and Clement, {Meredith E.} and Kuinkel, {Batu K.Sharma} and Felicia Ruffin and Flores, {Anthony R.} and Howard Levinson and Shelburne, {Samuel A.} and Zack Moore and Fowler, {Vance G.}",
note = "Funding Information: This work was supported by National Institute of Allergy and Infectious Diseases (grant R01AI089891 [to S. A. S.]; grants K24-AI093969 and R01-AI068804 [to V. G. F.]) and MD Anderson Cancer Center (MDACC) Bioinformatics Shared Resource support grant P30 CA016672 from the National Cancer Institute. J. G. P. is supported by the MDACC Odyssey Program and CFP Foundation. Publisher Copyright: {\textcopyright} The Author 2016. Published by Oxford University Press on behalf of the Infectious Diseases Society of America. Copyright: Copyright 2018 Elsevier B.V., All rights reserved.",
year = "2016",
month = jan,
day = "1",
doi = "10.1093/ofid/ofw042",
language = "English (US)",
volume = "3",
journal = "Open Forum Infectious Diseases",
issn = "2328-8957",
publisher = "Oxford University Press",
number = "1",
}