Aortitis and aortic occlusion in crohn disease

Charline Delay, Adeline Schwein, Anne Lejay, Sébastien Gaertner, Boris Aleil, Fabien Thaveau, Yannick Georg, Nabil Chakfe

Research output: Contribution to journalArticlepeer-review

4 Scopus citations


Patients with Crohn disease (CD) or ulcerative colitis are known to be at increased risk of arterial thromboembolic complications. We report the case of a 33-year-old woman suffering from CD for 19 years who presented lower limb claudication. Computed tomography scan revealed an aortoiliac occlusion extending from the level of the inferior mesenteric artery to both iliac bifurcations. Endovascular recanalization was attempted as a first option but failed. We then performed an aortobi-femoral bypass through a left retroperitoneal approach that allowed a total relief of the symptoms. Histologic study of the aorta demonstrated a nonspecific aortitis with lymphohistiocytic cell infiltration in the media and adventitia tunica. There was no signs of associated vasculitis. At the light of a literature review, we discussed our surgical strategy and the inflammation of the aortic wall as local factor of thrombosis that has never been previously described.

Original languageEnglish (US)
Pages (from-to)365.e5-365.e9
JournalAnnals of Vascular Surgery
Issue number2
StatePublished - Feb 1 2015

ASJC Scopus subject areas

  • Surgery
  • Cardiology and Cardiovascular Medicine


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