Antimicrobial factors and bacterial correlation in chronic otitis media with effusion

R. W. Lang; Y. S. Liu; D. J. Lim; H. G. Birck

doi:10.1177/00034894760850s227

Antimicrobial factors and bacterial correlation in chronic otitis media with effusion

R. W. Lang, Y. S. Liu, D. J. Lim, H. G. Birck

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15 Scopus citations

Abstract

Analyses of effusions and sera from patients with otitis media with effusion demonstrated local production in the middle ear of lysozyme, IgA and IgG. The effusion IgM was markedly elevated in some patients, also indicating local production. Complement C₃ with rare exception was significantly lower in effusions than sera, suggesting utilization of complement in the middle ear, perhaps in conjunction with antibodies. The presence of high levels of lysozyme and immunoglobulins in effusions correlates with the low isolation rate of microorganisms in culture and may influence survival of organisms in the middle ear.

Original language	English (US)
Pages (from-to)	145-151
Number of pages	7
Journal	Annals of Otology, Rhinology and Laryngology
Volume	85
Issue number	Sup.25
DOIs	https://doi.org/10.1177/00034894760850s227
State	Published - 1976

ASJC Scopus subject areas

Otorhinolaryngology

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abstract = "Analyses of effusions and sera from patients with otitis media with effusion demonstrated local production in the middle ear of lysozyme, IgA and IgG. The effusion IgM was markedly elevated in some patients, also indicating local production. Complement C3 with rare exception was significantly lower in effusions than sera, suggesting utilization of complement in the middle ear, perhaps in conjunction with antibodies. The presence of high levels of lysozyme and immunoglobulins in effusions correlates with the low isolation rate of microorganisms in culture and may influence survival of organisms in the middle ear.",

author = "Lang, {R. W.} and Liu, {Y. S.} and Lim, {D. J.} and Birck, {H. G.}",

year = "1976",

doi = "10.1177/00034894760850s227",

language = "English (US)",

volume = "85",

pages = "145--151",

journal = "Annals of Otology, Rhinology and Laryngology",

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T1 - Antimicrobial factors and bacterial correlation in chronic otitis media with effusion

AU - Lang, R. W.

AU - Liu, Y. S.

AU - Lim, D. J.

AU - Birck, H. G.

PY - 1976

Y1 - 1976

N2 - Analyses of effusions and sera from patients with otitis media with effusion demonstrated local production in the middle ear of lysozyme, IgA and IgG. The effusion IgM was markedly elevated in some patients, also indicating local production. Complement C3 with rare exception was significantly lower in effusions than sera, suggesting utilization of complement in the middle ear, perhaps in conjunction with antibodies. The presence of high levels of lysozyme and immunoglobulins in effusions correlates with the low isolation rate of microorganisms in culture and may influence survival of organisms in the middle ear.

AB - Analyses of effusions and sera from patients with otitis media with effusion demonstrated local production in the middle ear of lysozyme, IgA and IgG. The effusion IgM was markedly elevated in some patients, also indicating local production. Complement C3 with rare exception was significantly lower in effusions than sera, suggesting utilization of complement in the middle ear, perhaps in conjunction with antibodies. The presence of high levels of lysozyme and immunoglobulins in effusions correlates with the low isolation rate of microorganisms in culture and may influence survival of organisms in the middle ear.

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AN - SCOPUS:0017078123

SN - 0003-4894

VL - 85

SP - 145

EP - 151

JO - Annals of Otology, Rhinology and Laryngology

JF - Annals of Otology, Rhinology and Laryngology

IS - Sup.25

ER -

Antimicrobial factors and bacterial correlation in chronic otitis media with effusion

Abstract

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