Antimicrobial activities of beta-lactam antibiotics and gentamicin against penicillin-susceptible and penicillin-resistant pneumococci

M. E. Gross, K. P. Giron, J. D. Septimus, E. O. Mason, D. M. Musher

Research output: Contribution to journalArticle

21 Scopus citations

Abstract

The MICs of penicillin and cefotaxime for a range of penicillin- susceptible and penicillin-resistant isolates of Streptococcus pneumoniae were unchanged by the addition of gentamicin. In time-kill studies the rate of killing was greater for 18 of 20 isolates in the presence of gentamicin. However, mean differences in killing after 6 h of incubation were modest, not exceeding 1 log10 unit.

Original languageEnglish (US)
Pages (from-to)1166-1168
Number of pages3
JournalAntimicrobial Agents and Chemotherapy
Volume39
Issue number5
DOIs
StatePublished - 1995

ASJC Scopus subject areas

  • Pharmacology
  • Pharmacology (medical)
  • Infectious Diseases

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