Antigen detection in cerebrospinal fluid-Pros and cons

Sheldon Kaplan

Research output: Contribution to journalArticlepeer-review

24 Scopus citations


Over the past decade, rapid diagnostic techniques for detection of bacterial polysaccharide antigens have been developed and successfully applied in the clinical setting. Currently, countercurrent immunoelectrophoresis, latex particle agglutination, and coagglutination are the techniques most used in microbiology laboratories. Enzyme immunoassays may become more practical in the future. Quantitation of antigen concentration in cerebrospinal fluid provides prognostic information at the time of admission. This review summarizes the advantages, disadvantages, and clinical applications of these techniques.

Original languageEnglish (US)
Pages (from-to)109-118
Number of pages10
JournalThe American journal of medicine
Issue number1 PART 2
StatePublished - Jul 28 1983

ASJC Scopus subject areas

  • Medicine(all)


Dive into the research topics of 'Antigen detection in cerebrospinal fluid-Pros and cons'. Together they form a unique fingerprint.

Cite this