Abstract
IL-9-producing cytotoxic T (Tc9) cells represent a unique CD8+ T-cell subset. These long-lived immune cells possess the capacity to acquire effector function and home to tumor tissues after adoptive transfer. IL-9 is indispensable for Tc9-mediated superior antitumor response. These findings are highly significant and crucial to achieve advances in T cell-based adoptive therapies.
| Original language | English (US) |
|---|---|
| Pages (from-to) | e28542 |
| Journal | OncoImmunology |
| Volume | 3 |
| DOIs | |
| State | Published - 2014 |
Divisions RO
- Medical Oncology