Anticancer Tc9 cells: Long-lived tumor-killing T cells for adoptive therapy

Yong Lu, Qiang Wang, Qing Yi

Research output: Contribution to journalArticle

Abstract

IL-9-producing cytotoxic T (Tc9) cells represent a unique CD8+ T-cell subset. These long-lived immune cells possess the capacity to acquire effector function and home to tumor tissues after adoptive transfer. IL-9 is indispensable for Tc9-mediated superior antitumor response. These findings are highly significant and crucial to achieve advances in T cell-based adoptive therapies.

Original languageEnglish (US)
Pages (from-to)e28542
JournalOncoImmunology
Volume3
DOIs
StatePublished - 2014

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