Anticancer Tc9 cells: Long-lived tumor-killing T cells for adoptive therapy

Yong Lu; Qiang Wang; Qing Yi

doi:10.4161/onci.28542

Anticancer Tc9 cells: Long-lived tumor-killing T cells for adoptive therapy

Yong Lu, Qiang Wang, Qing Yi

Research output: Contribution to journal › Article › peer-review

Abstract

IL-9-producing cytotoxic T (Tc9) cells represent a unique CD8+ T-cell subset. These long-lived immune cells possess the capacity to acquire effector function and home to tumor tissues after adoptive transfer. IL-9 is indispensable for Tc9-mediated superior antitumor response. These findings are highly significant and crucial to achieve advances in T cell-based adoptive therapies.

Original language	English (US)
Pages (from-to)	e28542
Journal	OncoImmunology
Volume	3
DOIs	https://doi.org/10.4161/onci.28542
State	Published - 2014

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title = "Anticancer Tc9 cells: Long-lived tumor-killing T cells for adoptive therapy",

abstract = "IL-9-producing cytotoxic T (Tc9) cells represent a unique CD8+ T-cell subset. These long-lived immune cells possess the capacity to acquire effector function and home to tumor tissues after adoptive transfer. IL-9 is indispensable for Tc9-mediated superior antitumor response. These findings are highly significant and crucial to achieve advances in T cell-based adoptive therapies.",

author = "Yong Lu and Qiang Wang and Qing Yi",

year = "2014",

doi = "10.4161/onci.28542",

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T1 - Anticancer Tc9 cells

T2 - Long-lived tumor-killing T cells for adoptive therapy

AU - Lu, Yong

AU - Wang, Qiang

AU - Yi, Qing

PY - 2014

Y1 - 2014

N2 - IL-9-producing cytotoxic T (Tc9) cells represent a unique CD8+ T-cell subset. These long-lived immune cells possess the capacity to acquire effector function and home to tumor tissues after adoptive transfer. IL-9 is indispensable for Tc9-mediated superior antitumor response. These findings are highly significant and crucial to achieve advances in T cell-based adoptive therapies.

AB - IL-9-producing cytotoxic T (Tc9) cells represent a unique CD8+ T-cell subset. These long-lived immune cells possess the capacity to acquire effector function and home to tumor tissues after adoptive transfer. IL-9 is indispensable for Tc9-mediated superior antitumor response. These findings are highly significant and crucial to achieve advances in T cell-based adoptive therapies.

U2 - 10.4161/onci.28542

DO - 10.4161/onci.28542

M3 - Article

C2 - 25054087

SN - 2162-4011

VL - 3

SP - e28542

JO - OncoImmunology

JF - OncoImmunology

ER -

Anticancer Tc9 cells: Long-lived tumor-killing T cells for adoptive therapy

Abstract

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