Anticancer Activities of Tumor-killing Nanorobots

Suping Li; Qiao Jiang; Baoquan Ding; Guangjun Nie

doi:10.1016/j.tibtech.2019.01.010

Anticancer Activities of Tumor-killing Nanorobots

Suping Li, Qiao Jiang, Baoquan Ding, Guangjun Nie

Research output: Contribution to journal › Short survey › peer-review

33 Scopus citations

Abstract

Pharmaceutical uses of cancer therapeutics, such as intravenous thrombin to elicit blood coagulation, have been hampered by lack of tumor specificity. Based on rapid progress in DNA origami-based machines capable of transporting molecular payloads, DNA nanorobots have been constructed to specifically deliver therapeutic agents into tumor vessels.

Original language	English (US)
Pages (from-to)	573-577
Number of pages	5
Journal	Trends in Biotechnology
Volume	37
Issue number	6
DOIs	https://doi.org/10.1016/j.tibtech.2019.01.010
State	Published - Jun 2019

Keywords

DNA nanorobot
active tumor targeting
thrombin
vascular infarction

ASJC Scopus subject areas

Biotechnology
Bioengineering

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10.1016/j.tibtech.2019.01.010

Cite this

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title = "Anticancer Activities of Tumor-killing Nanorobots",

abstract = "Pharmaceutical uses of cancer therapeutics, such as intravenous thrombin to elicit blood coagulation, have been hampered by lack of tumor specificity. Based on rapid progress in DNA origami-based machines capable of transporting molecular payloads, DNA nanorobots have been constructed to specifically deliver therapeutic agents into tumor vessels.",

keywords = "DNA nanorobot, active tumor targeting, thrombin, vascular infarction",

author = "Suping Li and Qiao Jiang and Baoquan Ding and Guangjun Nie",

note = "Publisher Copyright: {\textcopyright} 2019 Elsevier Ltd",

year = "2019",

month = jun,

doi = "10.1016/j.tibtech.2019.01.010",

language = "English (US)",

volume = "37",

pages = "573--577",

journal = "Trends in Biotechnology",

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TY - JOUR

T1 - Anticancer Activities of Tumor-killing Nanorobots

AU - Li, Suping

AU - Jiang, Qiao

AU - Ding, Baoquan

AU - Nie, Guangjun

PY - 2019/6

Y1 - 2019/6

N2 - Pharmaceutical uses of cancer therapeutics, such as intravenous thrombin to elicit blood coagulation, have been hampered by lack of tumor specificity. Based on rapid progress in DNA origami-based machines capable of transporting molecular payloads, DNA nanorobots have been constructed to specifically deliver therapeutic agents into tumor vessels.

AB - Pharmaceutical uses of cancer therapeutics, such as intravenous thrombin to elicit blood coagulation, have been hampered by lack of tumor specificity. Based on rapid progress in DNA origami-based machines capable of transporting molecular payloads, DNA nanorobots have been constructed to specifically deliver therapeutic agents into tumor vessels.

KW - DNA nanorobot

KW - active tumor targeting

KW - thrombin

KW - vascular infarction

UR - https://www.scopus.com/pages/publications/85062086755

UR - https://www.scopus.com/inward/citedby.url?scp=85062086755&partnerID=8YFLogxK

U2 - 10.1016/j.tibtech.2019.01.010

DO - 10.1016/j.tibtech.2019.01.010

M3 - Short survey

C2 - 30826094

AN - SCOPUS:85062086755

SN - 0167-7799

VL - 37

SP - 573

EP - 577

JO - Trends in Biotechnology

JF - Trends in Biotechnology

IS - 6

ER -

Anticancer Activities of Tumor-killing Nanorobots

Abstract

Keywords

ASJC Scopus subject areas

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