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Antibody class switch recombination: Roles for switch sequences and mismatch repair proteins

Irene M. Min, Erik Selsing

Research output: Contribution to journalReview articlepeer-review

Abstract

Mechanisms and targeting of antibody class switch DNA recombination are reviewed. Particular emphasis is on the roles for the DNA sequences comprising switch (S) regions, including the S-region tandem repeats, and on the roles of proteins that are involved in both DNA mismatch repair and in class switch recombination.

Original languageEnglish (US)
Pages (from-to)297-328
Number of pages32
JournalAdvances in Immunology
Volume87
DOIs
StatePublished - 2005

ASJC Scopus subject areas

  • Immunology and Allergy
  • Immunology

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