Antibody class switch recombination: Roles for switch sequences and mismatch repair proteins

Irene M. Min, Erik Selsing

Research output: Contribution to journalReview articlepeer-review

16 Scopus citations

Abstract

Mechanisms and targeting of antibody class switch DNA recombination are reviewed. Particular emphasis is on the roles for the DNA sequences comprising switch (S) regions, including the S-region tandem repeats, and on the roles of proteins that are involved in both DNA mismatch repair and in class switch recombination.

Original languageEnglish (US)
Pages (from-to)297-328
Number of pages32
JournalAdvances in Immunology
Volume87
DOIs
StatePublished - 2005

ASJC Scopus subject areas

  • Immunology and Allergy
  • Immunology

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