Anti-neutrophil cytoplasmic autoantibodies in a child with pauci-immune necrotizing and crescentic glomerulonephritis

Lou Anne Baldree; Lillian Gaber; Charles P. McKay

doi:10.1007/BF00867482

Anti-neutrophil cytoplasmic autoantibodies in a child with pauci-immune necrotizing and crescentic glomerulonephritis

Lou Anne Baldree, Lillian Gaber, Charles P. McKay

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15 Scopus citations

Abstract

We report a case of pauci-immune, necrotizing and crescentic glomerulonephritis in a 10-year-old child initially thought to have Henoch-Schönlein purpura. The diagnosis of a Wegener's granulomatosis-microscopic polyarteritis disorder was made on the basis of clinical presentation and a positive anti-neutrophil cytoplasmic auto-antibody (ANCA). This case illustrates the usefulness of the ANCA in the diagnosis and management of childhood vasculitides.

Original language	English (US)
Pages (from-to)	296-299
Number of pages	4
Journal	Pediatric Nephrology
Volume	5
Issue number	3
DOIs	https://doi.org/10.1007/BF00867482
State	Published - May 1 1991

Keywords

ANCA-associated glomerulonephritis
Anti-nuclear cytoplasmic autoantibody (ANCA)
Microscopic polyarteritis
Necrotizing glomerulonephritis
Vasculitis
Wegener's granulomatosis

ASJC Scopus subject areas

Pediatrics, Perinatology, and Child Health
Nephrology

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title = "Anti-neutrophil cytoplasmic autoantibodies in a child with pauci-immune necrotizing and crescentic glomerulonephritis",

abstract = "We report a case of pauci-immune, necrotizing and crescentic glomerulonephritis in a 10-year-old child initially thought to have Henoch-Sch{\"o}nlein purpura. The diagnosis of a Wegener's granulomatosis-microscopic polyarteritis disorder was made on the basis of clinical presentation and a positive anti-neutrophil cytoplasmic auto-antibody (ANCA). This case illustrates the usefulness of the ANCA in the diagnosis and management of childhood vasculitides.",

keywords = "ANCA-associated glomerulonephritis, Anti-nuclear cytoplasmic autoantibody (ANCA), Microscopic polyarteritis, Necrotizing glomerulonephritis, Vasculitis, Wegener's granulomatosis",

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T1 - Anti-neutrophil cytoplasmic autoantibodies in a child with pauci-immune necrotizing and crescentic glomerulonephritis

AU - Baldree, Lou Anne

AU - Gaber, Lillian

AU - McKay, Charles P.

PY - 1991/5/1

Y1 - 1991/5/1

N2 - We report a case of pauci-immune, necrotizing and crescentic glomerulonephritis in a 10-year-old child initially thought to have Henoch-Schönlein purpura. The diagnosis of a Wegener's granulomatosis-microscopic polyarteritis disorder was made on the basis of clinical presentation and a positive anti-neutrophil cytoplasmic auto-antibody (ANCA). This case illustrates the usefulness of the ANCA in the diagnosis and management of childhood vasculitides.

AB - We report a case of pauci-immune, necrotizing and crescentic glomerulonephritis in a 10-year-old child initially thought to have Henoch-Schönlein purpura. The diagnosis of a Wegener's granulomatosis-microscopic polyarteritis disorder was made on the basis of clinical presentation and a positive anti-neutrophil cytoplasmic auto-antibody (ANCA). This case illustrates the usefulness of the ANCA in the diagnosis and management of childhood vasculitides.

KW - ANCA-associated glomerulonephritis

KW - Anti-nuclear cytoplasmic autoantibody (ANCA)

KW - Microscopic polyarteritis

KW - Necrotizing glomerulonephritis

KW - Vasculitis

KW - Wegener's granulomatosis

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Anti-neutrophil cytoplasmic autoantibodies in a child with pauci-immune necrotizing and crescentic glomerulonephritis

Abstract

Keywords

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