We report a case of pauci-immune, necrotizing and crescentic glomerulonephritis in a 10-year-old child initially thought to have Henoch-Schönlein purpura. The diagnosis of a Wegener's granulomatosis-microscopic polyarteritis disorder was made on the basis of clinical presentation and a positive anti-neutrophil cytoplasmic auto-antibody (ANCA). This case illustrates the usefulness of the ANCA in the diagnosis and management of childhood vasculitides.
- ANCA-associated glomerulonephritis
- Anti-nuclear cytoplasmic autoantibody (ANCA)
- Microscopic polyarteritis
- Necrotizing glomerulonephritis
- Wegener's granulomatosis
ASJC Scopus subject areas
- Pediatrics, Perinatology, and Child Health