Anti-asialo-GM1 and GD1a variant of miller fisher variant of Guillain-Barré syndrome

Michael L. Morgan, Nathan Law, Angelina Espino Barros Palau, Umair Saeed, Sushma Yalmanchili, Andrew G. Lee

Research output: Contribution to journalArticlepeer-review

4 Scopus citations


We present a woman with acute onset of bilateral ophthalmoparesis and ataxia occurring 4 weeks after gastroenteritis. Serum antibody titers against asialo-GM1 and GD1a, typically associated with inflammatory axonal neuropathies, were elevated but titers against anti-GQ1b, the most commonly found antibody found in the Miller Fisher variant of Guillain-Barre syndrome were not. No other etiology for ophthalmoparesis was found despite extensive patient evaluation. Intravenous immunoglobulin was admin-istered, and the patient gradually improved over subsequent months. This case is unique for its antiganglioside antibody profile associated with Miller Fisher syndrome.

Original languageEnglish (US)
Pages (from-to)377-379
Number of pages3
JournalJournal of Neuro-Ophthalmology
Issue number4
StatePublished - Dec 8 2014

ASJC Scopus subject areas

  • Medicine(all)


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