Anterior Temporal Lobectomy and Medically Refractory Temporal Lobe Epilepsy of Childhood

Eli M. Mizrahi, Peter Kellaway, Robert G. Grossman, Paul A. Rutecki, Dawna Armstrong, Gayle Rettig, Susan Loewen

Research output: Contribution to journalArticlepeer-review

105 Scopus citations


The evaluation and outcome of 22 patients who had onset of complex partial seizures (CPS) of temporal lobe origin in childhood and subsequently underwent anterior temporal lobectomy are described. All patients showed improved seizure control; 81.8% had a reduction ≥95% in seizure frequency. However, many patients had difficulty adjusting to a seizure-free life. Psychosocial, behavioral, and educational problems occurred more frquently in patients whose surgery was delayed until adult life. We conclude that attempts should be made early in the course of CPS of childhood to determine whether the seizures are truly intractable to medical management so that surgical intervention can be expedited.

Original languageEnglish (US)
Pages (from-to)302-312
Number of pages11
Issue number3
StatePublished - Jun 1990


  • Anterior temporal lobectomy
  • Childhood epilepsy
  • Children
  • Complex partial seizures
  • Neurosurgery
  • Seizures
  • Temporal lobe epilepsy

ASJC Scopus subject areas

  • Clinical Neurology
  • Neuroscience(all)


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