Nyupptäckt östrogenreceptor: Öppnar nya behandlingsmöjligheter vid postklimakteriella symtom, osteoporos, ateroskleros, bröst- och prostatacancer

Translated title of the contribution: Another oestrogen receptor discovered; New treatment options for postmenopausal symptoms, osteoporosis, atherosclerosis, and breast and prostate cancer may be possible

Eva Enmark, Jan-Ake Gustafsson

Research output: Contribution to journalArticlepeer-review

6 Scopus citations

Abstract

A previously unknown oestrogen receptor, ERβ, has recently been isolated. ERβ is expressed in many important target tissues for oestrogen (ie, prostate, ovary, testis, and the cardiovascular and central nervous systems), and probably mediates many of the effects of oestrogens in the human body. Moreover, ERβ represents an interesting target for drug development, and ligands specific for the respective receptor subtype may offer interesting possibilities for the treatment of postmenopausal symptoms, and breast and prostate cancer, without many of the hitherto adverse side effects, such as the increased risk of endometrial cancer associated with hormone replacement therapy.

Translated title of the contributionAnother oestrogen receptor discovered; New treatment options for postmenopausal symptoms, osteoporosis, atherosclerosis, and breast and prostate cancer may be possible
Original languageSwedish
Pages (from-to)1945-1949
Number of pages5
JournalLakartidningen
Issue number17
StatePublished - Dec 1 1998

ASJC Scopus subject areas

  • Medicine(all)

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