Animal models of allergic bronchopulmonary aspergillosis

G. Grunig, D. B. Corry, R. L. Coffman, D. M. Rennick, V. P. Kurup

    Research output: Contribution to journalArticlepeer-review

    9 Scopus citations

    Abstract

    Animal models of ABPA provide an intriguing insight into disease pathogenesis across various species. In the mouse, the availability of gene-targeted animals allows for a detailed dissection of critical cells and cytokines that mediate immunopathology. T cells are the central effectors that ultimately induce lung pathology and airway hyperreactivity in murine ABPA.

    Original languageEnglish (US)
    Pages (from-to)661-679
    Number of pages19
    JournalImmunology and Allergy Clinics of North America
    Volume18
    Issue number3
    DOIs
    StatePublished - 1998

    ASJC Scopus subject areas

    • Immunology and Allergy
    • Immunology

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