Animal models of allergic bronchopulmonary aspergillosis

G. Grunig, D. B. Corry, R. L. Coffman, D. M. Rennick, V. P. Kurup

Research output: Contribution to journalArticlepeer-review

8 Scopus citations

Abstract

Animal models of ABPA provide an intriguing insight into disease pathogenesis across various species. In the mouse, the availability of gene-targeted animals allows for a detailed dissection of critical cells and cytokines that mediate immunopathology. T cells are the central effectors that ultimately induce lung pathology and airway hyperreactivity in murine ABPA.

Original languageEnglish (US)
Pages (from-to)661-679
Number of pages19
JournalImmunology and Allergy Clinics of North America
Volume18
Issue number3
DOIs
StatePublished - 1998

ASJC Scopus subject areas

  • Immunology and Allergy
  • Immunology

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