Abstract
Animal models of ABPA provide an intriguing insight into disease pathogenesis across various species. In the mouse, the availability of gene-targeted animals allows for a detailed dissection of critical cells and cytokines that mediate immunopathology. T cells are the central effectors that ultimately induce lung pathology and airway hyperreactivity in murine ABPA.
Original language | English (US) |
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Pages (from-to) | 661-679 |
Number of pages | 19 |
Journal | Immunology and Allergy Clinics of North America |
Volume | 18 |
Issue number | 3 |
DOIs | |
State | Published - 1998 |
ASJC Scopus subject areas
- Immunology and Allergy
- Immunology