Animal models in brain–computer interface research

Yu Tung Lo; Lei Jiang; Jordan L.W. Lam; Ben Woodington; Elise P.W. Jenkins; Vasileios Christopoulos; Darrin J. Lee; Yuxin Liu; Charles Y. Liu

doi:10.1038/s44222-025-00313-6

Animal models in brain–computer interface research

Yu Tung Lo, Lei Jiang, Jordan L.W. Lam, Ben Woodington, Elise P.W. Jenkins, Vasileios Christopoulos, Darrin J. Lee, Yuxin Liu, Charles Y. Liu

Research output: Contribution to journal › Comment/debate › peer-review

Abstract

The development of chronic implantable brain–computer interface devices requires extensive preclinical testing, for which various animal models can be used. However, bridging the translational gap requires strategic consideration of their brains’ physiological, anatomical and functional organization differences.

Original language	English (US)
Article number	1319
Journal	Nature Reviews Bioengineering
DOIs	https://doi.org/10.1038/s44222-025-00313-6
State	Accepted/In press - 2025

ASJC Scopus subject areas

Biophysics
Biomedical Engineering
Applied Microbiology and Biotechnology

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10.1038/s44222-025-00313-6

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title = "Animal models in brain–computer interface research",

abstract = "The development of chronic implantable brain–computer interface devices requires extensive preclinical testing, for which various animal models can be used. However, bridging the translational gap requires strategic consideration of their brains{\textquoteright} physiological, anatomical and functional organization differences.",

author = "Lo, {Yu Tung} and Lei Jiang and Lam, {Jordan L.W.} and Ben Woodington and Jenkins, {Elise P.W.} and Vasileios Christopoulos and Lee, {Darrin J.} and Yuxin Liu and Liu, {Charles Y.}",

note = "Publisher Copyright: {\textcopyright} Springer Nature Limited 2025.",

year = "2025",

doi = "10.1038/s44222-025-00313-6",

language = "English (US)",

journal = "Nature Reviews Bioengineering",

issn = "2731-6092",

publisher = "Springer Nature",

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T1 - Animal models in brain–computer interface research

AU - Lo, Yu Tung

AU - Jiang, Lei

AU - Lam, Jordan L.W.

AU - Woodington, Ben

AU - Jenkins, Elise P.W.

AU - Christopoulos, Vasileios

AU - Lee, Darrin J.

AU - Liu, Yuxin

AU - Liu, Charles Y.

PY - 2025

Y1 - 2025

N2 - The development of chronic implantable brain–computer interface devices requires extensive preclinical testing, for which various animal models can be used. However, bridging the translational gap requires strategic consideration of their brains’ physiological, anatomical and functional organization differences.

AB - The development of chronic implantable brain–computer interface devices requires extensive preclinical testing, for which various animal models can be used. However, bridging the translational gap requires strategic consideration of their brains’ physiological, anatomical and functional organization differences.

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DO - 10.1038/s44222-025-00313-6

M3 - Comment/debate

AN - SCOPUS:105004473826

SN - 2731-6092

JO - Nature Reviews Bioengineering

JF - Nature Reviews Bioengineering

M1 - 1319

ER -

Animal models in brain–computer interface research

Abstract

ASJC Scopus subject areas

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