Angiotensin Converting Enzyme Inhibition and Mortality in Pulmonary Hypertension Associated With Chronic Obstructive Pulmonary Disease (PH-COPD)

PVRI-GoDeep-Consortium

doi:10.1002/pul2.70348

Angiotensin Converting Enzyme Inhibition and Mortality in Pulmonary Hypertension Associated With Chronic Obstructive Pulmonary Disease (PH-COPD)

PVRI-GoDeep-Consortium

Research output: Contribution to journal › Letter › peer-review

Abstract

In 567 PH-COPD patients from the PVRI GoDeep Meta-Registry, ACE inhibitor use was associated with improved survival only in severe PH (PVR > 5 WU), supporting prospective trials targeting this high-risk subgroup.

Original language	English (US)
Article number	e70348
Journal	Pulmonary Circulation
Volume	16
Issue number	3
DOIs	https://doi.org/10.1002/pul2.70348
State	Published - Jul 2026

ASJC Scopus subject areas

Pulmonary and Respiratory Medicine

Divisions

Pulmonary, Critical Care and Sleep Medicine

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10.1002/pul2.70348

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@article{514c808831184e899cf6064cb7504dcf,

title = "Angiotensin Converting Enzyme Inhibition and Mortality in Pulmonary Hypertension Associated With Chronic Obstructive Pulmonary Disease (PH-COPD)",

abstract = "In 567 PH-COPD patients from the PVRI GoDeep Meta-Registry, ACE inhibitor use was associated with improved survival only in severe PH (PVR > 5 WU), supporting prospective trials targeting this high-risk subgroup.",

author = "PVRI-GoDeep-Consortium and Athiththan Yogeswaran and Meike F{\"u}nderich and Katharina Wendlandt and Annis, \{Jeffrey S.\} and Evan Brittain and Eichstaedt, \{Christina A.\} and Ekkehard Gr{\"u}nig and Cajigas, \{Hector R.\} and Robert Frantz and Sweatt, \{Andrew J.\} and Zamanian, \{Roham T.\} and Friedrich Grimminger and Jochen Wilhelm and Ghofrani, \{Hossein Ardeschir\} and Khodr Tello and Werner Seeger and Mauro Acquaro and Ghouleh, \{Imad Al\} and James Anderson and Anastasia Anthi and Alexandra Arvanitaki and Aparna Balasubramanian and Felix Ballmann and Barbera, \{Joan Albert\} and Bogaard, \{Harm Jan\} and Hugh Buzacott and John Cannon and Demircan Ceren and Chan, \{Stephen Y.\} and Utrilla, \{Alejandro Cruz\} and Victoria Damonte and Bie, \{Eckart De\} and Figueroa, \{Juliana De Luque\} and Effrosyni Dima and Philipp Douschan and Nathan Dwyer and Diego Echazarreta and Jean Elwing and Subias, \{Pilar Escribano\} and Kai F{\"o}rster and Marlize Frauendorf and Stefano Ghio and George Giannakoulas and Lars Harbaum and Hassoun, \{Paul M.\} and Melanie Heberling and Anne Hilgendorff and Luke Howard and Patrick Janetzko and Sandeep Sahay",

note = "Publisher Copyright: {\textcopyright} 2026 The Author(s). Pulmonary Circulation published by John Wiley \& Sons Ltd on behalf of Pulmonary Vascular Research Institute.",

year = "2026",

month = jul,

doi = "10.1002/pul2.70348",

language = "English (US)",

volume = "16",

journal = "Pulmonary Circulation",

issn = "2045-8932",

publisher = "Wiley",

number = "3",

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TY - JOUR

T1 - Angiotensin Converting Enzyme Inhibition and Mortality in Pulmonary Hypertension Associated With Chronic Obstructive Pulmonary Disease (PH-COPD)

AU - PVRI-GoDeep-Consortium

AU - Yogeswaran, Athiththan

AU - Fünderich, Meike

AU - Wendlandt, Katharina

AU - Annis, Jeffrey S.

AU - Brittain, Evan

AU - Eichstaedt, Christina A.

AU - Grünig, Ekkehard

AU - Cajigas, Hector R.

AU - Frantz, Robert

AU - Sweatt, Andrew J.

AU - Zamanian, Roham T.

AU - Grimminger, Friedrich

AU - Wilhelm, Jochen

AU - Ghofrani, Hossein Ardeschir

AU - Tello, Khodr

AU - Seeger, Werner

AU - Acquaro, Mauro

AU - Ghouleh, Imad Al

AU - Anderson, James

AU - Anthi, Anastasia

AU - Arvanitaki, Alexandra

AU - Balasubramanian, Aparna

AU - Ballmann, Felix

AU - Barbera, Joan Albert

AU - Bogaard, Harm Jan

AU - Buzacott, Hugh

AU - Cannon, John

AU - Ceren, Demircan

AU - Chan, Stephen Y.

AU - Utrilla, Alejandro Cruz

AU - Damonte, Victoria

AU - Bie, Eckart De

AU - Figueroa, Juliana De Luque

AU - Dima, Effrosyni

AU - Douschan, Philipp

AU - Dwyer, Nathan

AU - Echazarreta, Diego

AU - Elwing, Jean

AU - Subias, Pilar Escribano

AU - Förster, Kai

AU - Frauendorf, Marlize

AU - Ghio, Stefano

AU - Giannakoulas, George

AU - Harbaum, Lars

AU - Hassoun, Paul M.

AU - Heberling, Melanie

AU - Hilgendorff, Anne

AU - Howard, Luke

AU - Janetzko, Patrick

AU - Sahay, Sandeep

PY - 2026/7

Y1 - 2026/7

N2 - In 567 PH-COPD patients from the PVRI GoDeep Meta-Registry, ACE inhibitor use was associated with improved survival only in severe PH (PVR > 5 WU), supporting prospective trials targeting this high-risk subgroup.

AB - In 567 PH-COPD patients from the PVRI GoDeep Meta-Registry, ACE inhibitor use was associated with improved survival only in severe PH (PVR > 5 WU), supporting prospective trials targeting this high-risk subgroup.

UR - https://www.scopus.com/pages/publications/105044826179

UR - https://www.scopus.com/inward/citedby.url?scp=105044826179&partnerID=8YFLogxK

U2 - 10.1002/pul2.70348

DO - 10.1002/pul2.70348

M3 - Letter

AN - SCOPUS:105044826179

SN - 2045-8932

VL - 16

JO - Pulmonary Circulation

JF - Pulmonary Circulation

IS - 3

M1 - e70348

ER -

Angiotensin Converting Enzyme Inhibition and Mortality in Pulmonary Hypertension Associated With Chronic Obstructive Pulmonary Disease (PH-COPD)

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