TY - JOUR
T1 - Angiomatoid malignant fibrous histiocytoma
T2 - Flow cytometric DNA analysis of six cases
AU - El‐Naggar, Adel K.
AU - Ro, Jae
AU - Ayala, Alberto
AU - Hinchey, William W.
AU - Abdul‐Karim, Fadi W.
AU - Batsakis, John G.
PY - 1989/1/1
Y1 - 1989/1/1
N2 - Using flow cytometry, we examined the DNA content of six angiomatoid 'malignant' fibrous histiocytomas (AMFH), seven nonangiomatoid MFH, and seven myxoid variants of MFH. All six AMFHs were diploid. All nonangiomatoid MFHs and six of seven of the myxoid variant were aneuploid. The clinical course, histological appearance, and ploidy pattern of AMFH are distinctly different from other MFH variants. These differences strongly suggest that AMFH is at the benign end of the clinicobiologic spectrum manifested by 'malignant' fibrous histiocytomas.
AB - Using flow cytometry, we examined the DNA content of six angiomatoid 'malignant' fibrous histiocytomas (AMFH), seven nonangiomatoid MFH, and seven myxoid variants of MFH. All six AMFHs were diploid. All nonangiomatoid MFHs and six of seven of the myxoid variant were aneuploid. The clinical course, histological appearance, and ploidy pattern of AMFH are distinctly different from other MFH variants. These differences strongly suggest that AMFH is at the benign end of the clinicobiologic spectrum manifested by 'malignant' fibrous histiocytomas.
KW - DNA content
KW - aneuploid
KW - diploid
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U2 - 10.1002/jso.2930400314
DO - 10.1002/jso.2930400314
M3 - Article
C2 - 2537444
AN - SCOPUS:0024556548
VL - 40
SP - 201
EP - 204
JO - Journal of Surgical Oncology
JF - Journal of Surgical Oncology
SN - 0022-4790
IS - 3
ER -