Angiomatoid malignant fibrous histiocytoma: Flow cytometric DNA analysis of six cases

Adel K. El‐Naggar, Jae Ro, Alberto Ayala, William W. Hinchey, Fadi W. Abdul‐Karim, John G. Batsakis

Research output: Contribution to journalArticle

15 Scopus citations

Abstract

Using flow cytometry, we examined the DNA content of six angiomatoid 'malignant' fibrous histiocytomas (AMFH), seven nonangiomatoid MFH, and seven myxoid variants of MFH. All six AMFHs were diploid. All nonangiomatoid MFHs and six of seven of the myxoid variant were aneuploid. The clinical course, histological appearance, and ploidy pattern of AMFH are distinctly different from other MFH variants. These differences strongly suggest that AMFH is at the benign end of the clinicobiologic spectrum manifested by 'malignant' fibrous histiocytomas.

Original languageEnglish (US)
Pages (from-to)201-204
Number of pages4
JournalJournal of Surgical Oncology
Volume40
Issue number3
DOIs
StatePublished - Jan 1 1989

Keywords

  • DNA content
  • aneuploid
  • diploid

ASJC Scopus subject areas

  • Surgery
  • Oncology

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