Aneurysm growth and thrombus formation in the basilar artery

Liang Der Jou, David Saloner, Brad Dispensa, William L. Young

Research output: Contribution to journalConference articlepeer-review


Modifying aneurysm hemodynamics may reduce the likelihood of aneurysm rupture. In this study, hemodynamics in a growing aneurysm and a thrombus-developing basilar aneurysm is studied. The locations of thrombus and growth were identified by co-registering MR images of aneurysms at two different times. The thrombus (∼6mm) appeared at the superior side of the aneurysm, where the flow impinged on the wall, and aneurysm growth (∼3mm) was found at the inferior side (lower part) of the aneurysm. The wall shear stress was calculated from flow simulations. The location of growth has a very low wall shear stress (< 0.01N/m2). The change of hemodynamics during thrombus development was not significant, but the thickest thrombus was shown to have a wall shear stress level between 0.2 and 1N/m2.

Original languageEnglish (US)
Article numberIMECE2004-62424
Pages (from-to)65-66
Number of pages2
JournalAdvances in Bioengineering, BED
StatePublished - 2004
Event2004 ASME International Mechanical Engineering Congress and Exposition, IMECE - Anaheim, CA, United States
Duration: Nov 13 2004Nov 19 2004


  • Cerebral aneurysms
  • Hemodynamics
  • Thrombus

ASJC Scopus subject areas

  • Engineering(all)


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