ANCA-mediated crescentic glomerulonephritis with linear deposition of IgG along the glomerular basement membrane.

Wiroon Sangsiraprapha, Luan Truong, Sreedhar Mandayam

Research output: Contribution to journalArticle

1 Scopus citations

Abstract

Antineutrophil cytoplasmic antibody (ANCA)-associated vasculitides is an important cause of rapidly progressive glomerulonephritides (RPGN), and they are classically described as pauci-immune diseases as evidenced by the absence of immune deposits on immunofluoresence microscopy of the kidney biopsy. We report two patients with RPGN, pulmonary-renal syndrome, positive ANCA serology and linear Immunoglobulin G (IgG) staining on glomerular basement membrane in the absence of detectable anti-glomerular basement membrane (anti-GBM) antibodies in the serum.

Original languageEnglish (US)
Pages (from-to)634-637
Number of pages4
JournalSaudi journal of kidney diseases and transplantation : an official publication of the Saudi Center for Organ Transplantation, Saudi Arabia
Volume25
Issue number3
DOIs
StatePublished - May 2014

ASJC Scopus subject areas

  • Medicine(all)

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