Anatomical success rate after primary three-port lens-sparing vitrectomy in stage 5 retinopathy of prematurity

Rohit R. Lakhanpal, Regina L. Sun, Thomas A. Albini, Eric Holz

Research output: Contribution to journalReview articlepeer-review

37 Scopus citations


PURPOSE: To assess the anatomical success rate after three-port lens-sparing vitrectomy (LSV) in stage 5 (total) retinal detachments secondary to retinopathy of prematurity. METHODS: In a retrospective, interventional, single-surgeon, consecutive case series, the records of 33 eyes of 21 patients presenting with stage 5 retinal detachment secondary to retinopathy of prematurity who underwent primary three-port LSV from February 1998 to January 2004 were evaluated. Twenty-one eyes (63.6%) had open anteriorly-open posteriorly and 12 (36.4%) had open anteriorly-narrow posteriorly in terms of anatomical configuration. The main outcome measure, retinal reattachment, was reviewed at final follow-up visits, which ranged from 6 months to 48 months (mean, 32 months) after LSV. RESULTS: Fifteen eyes (45.5%) maintained attachment and 18 eyes (54.5%) remained detached at the final visit. Open anteriorly-open posteriorly configuration eyes had a statistically significant higher anatomical success rate than eyes with an open anteriorly-narrow posteriorly configuration (P < 0.001). CONCLUSIONS: Three-port LSV may achieve anatomical success in stage 5 retinopathy of prematurity-related detachments. The open anteriorly-open posteriorly configuration portends a better prognosis; thus, surgery should be performed before closure of the posterior retina into a funnel configuration, if possible.

Original languageEnglish (US)
Pages (from-to)724-728
Number of pages5
Issue number7
StatePublished - Sep 1 2006


  • Funnel configuration
  • Lens-sparing vitrectomy (LSV)
  • Open anteriorly-narrow posteriorly configuration (ONC)
  • Open anteriorly-open posteriorly configuration (OOC)
  • Retinal reattachment
  • Retinopathy of prematurity
  • Stage 5
  • Three port
  • Vitrectomy

ASJC Scopus subject areas

  • Ophthalmology
  • Sensory Systems


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