TY - JOUR
T1 - Anaphylactoid reactions to radiocontrast agents
T2 - Prevention and treatment in the cardiac catheterization laboratory
AU - Nayak, Keshav R.
AU - White, Andrew A.
AU - Cavendish, Jeffrey J.
AU - Barker, Colin M.
AU - Kandzari, David E.
N1 - Copyright:
Copyright 2010 Elsevier B.V., All rights reserved.
PY - 2009/10
Y1 - 2009/10
N2 - The use of iodinated contrast agents for angiography dates back to the 1920s1. The initial prototype has undergone modifications to reduce the toxicity and discomfort associated with the early contrast molecules. More importantly, these changes have dramatically decreased the rate and risk for severe adverse reactions such as hypersensitivity and anaphylaxis. With over 15 million contrast-requiring procedures performed annually in the United States, it is important to understand the risk factors, pathogenesis, diagnosis, 2 prevention and treatment of contrast-induced anaphylactoid reactions. Reviews of adverse reactions are sparse in the cardiology literature, except for a landmark review in 1995 by Goss et al, which has served as the only practice guideline to date for cardiologists. 3In this report, we review the most recent literature to provide a guide for the general and interventional cardiologist in regards to the pretreatment and management of contrast-related reactions specifically in the cardiac catheterization laboratory.
AB - The use of iodinated contrast agents for angiography dates back to the 1920s1. The initial prototype has undergone modifications to reduce the toxicity and discomfort associated with the early contrast molecules. More importantly, these changes have dramatically decreased the rate and risk for severe adverse reactions such as hypersensitivity and anaphylaxis. With over 15 million contrast-requiring procedures performed annually in the United States, it is important to understand the risk factors, pathogenesis, diagnosis, 2 prevention and treatment of contrast-induced anaphylactoid reactions. Reviews of adverse reactions are sparse in the cardiology literature, except for a landmark review in 1995 by Goss et al, which has served as the only practice guideline to date for cardiologists. 3In this report, we review the most recent literature to provide a guide for the general and interventional cardiologist in regards to the pretreatment and management of contrast-related reactions specifically in the cardiac catheterization laboratory.
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M3 - Review article
C2 - 19805846
AN - SCOPUS:72649100847
SN - 1042-3931
VL - 21
SP - 548
EP - 551
JO - Journal of Invasive Cardiology
JF - Journal of Invasive Cardiology
IS - 10
ER -