Analysis of the hot spots of coated pits in live cells

Jia Deng, Henry Leung, Robert J. Elliott, Stephen T. Wong, Xiaobo Zhou

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Coated pits carry important information about plasma membrane and endosomes. They remove proteins and lipids from the plasma membrane and transport them to the endosomal compartment. It is of interest to get a thorough understanding of these pits. In this paper, we consider two kinds of proteins in coated pits: clathrin and AP-2. We propose a detection method to extract as many coated pits trajectories as possible. It is observed that we can predict whether or not a pit will appear at certain "hot spot" at a certain time.

Original languageEnglish (US)
Title of host publication2007 IEEE/NIH Life Science Systems and Applications Workshop, LISA
PublisherInstitute of Electrical and Electronics Engineers Inc.
Pages51-54
Number of pages4
ISBN (Print)9781424418138
DOIs
StatePublished - Jan 1 2007
Event2007 IEEE/NIH Life Science Systems and Applications Workshop, LISA - Bethesda, MD, United States
Duration: Nov 8 2007Nov 9 2007

Other

Other2007 IEEE/NIH Life Science Systems and Applications Workshop, LISA
CountryUnited States
CityBethesda, MD
Period11/8/0711/9/07

ASJC Scopus subject areas

  • Computer Science Applications
  • Information Systems

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