Abstract
High resolution photoplate mass spectrometry has been used to examine crude goat urine extracts to determine the fate of organochlorine xenobiotics in these animals. Using a direct introduction temperature controlled probe the crude urine extracts were analyzed and the presence of oxygenated metabolites of 4‐chlorobiphenyl and 4,4′‐dichlorobiphenyl were confirmed in goats; analyses of urine extracts from goats injected with the commercial Aroclor mixtures 1254 and 5460 confirmed the formation of oxygenated penta‐, tetra‐ and monochlorobiphenyl metabolites and an oxygenated dichloroterphenyl metabolite, respectively. This technique was particularly useful in the analysis of complex mixtures of metabolites.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 201-203 |
| Number of pages | 3 |
| Journal | Biological Mass Spectrometry |
| Volume | 2 |
| Issue number | 4 |
| DOIs | |
| State | Published - Aug 1975 |
ASJC Scopus subject areas
- Biochemistry
- Molecular Medicine