An XML message broker framework for exchange and integration of microarray data

Donny Tjandra, Stephen Wong, Weimin Shen, Brian Pulliam, Elaine Yu, Laura Esserman

Research output: Contribution to journalArticle

4 Scopus citations

Abstract

Motivation: Microarrays are an important research tool for the advancement of basic biological sciences. However this technology has yet to be integrated with clinical decision making. We have implemented an information framework based on the Microarray Gene Expression Markup Language (MAGE-ML) specification. We are using this framework to develop a test-bed integrated database application to identify genomic and imaging markers for diagnosis of breast cancer. Results: We developed extensible software architecture for retrieving data from different microarray databases using MAGE-ML and for combining microarray data with breast cancer image analysis and clinical data for correlation studies. The framework we developed will provide the necessary data integration to move microarray research from basic biological sciences to clinical applications.

Original languageEnglish (US)
Pages (from-to)1844-1845
Number of pages2
JournalBioinformatics
Volume19
Issue number14
DOIs
StatePublished - Sep 22 2003

ASJC Scopus subject areas

  • Statistics and Probability
  • Biochemistry
  • Molecular Biology
  • Computer Science Applications
  • Computational Theory and Mathematics
  • Computational Mathematics

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