An ultrastructural study of the guinea pig tectorial membrane 'type A' protofibril

Toshio Arima, David J. Lim, Hiroshi Kawaguchi, Yosabur Shibata, Takuya Uemura

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16 Scopus citations


Fine structural features of the 'type A' protofibrils in the guinea pig tectorial membrane were examined using negative staining and deep-etching techniques. Negative-stained samples of fragmented tectorial membrane were composed of several fine filamentous subunits showing the clear banding pattern of the type A protofibrils. Deep-etched replicas of the EGTA (ethylene glycol bis-N,N,N',N'-tetraacetic acid)-treated samples showed fine surface structure consisting of several linear arrays of filamentous elements on the extracellular fibrils, which is interpreted to be type A protofibrils.

Original languageEnglish (US)
Pages (from-to)289-292
Number of pages4
JournalHearing Research
Issue number3
StatePublished - Jul 1990


  • Collagen
  • Ear
  • Tectorial membrane
  • inner
  • type II

ASJC Scopus subject areas

  • Sensory Systems


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