TY - GEN
T1 - An image driven systems biology approach for neurodegenerative disease studies in the TSC-mTOR pathway
AU - Beck, Dominik
AU - Zhou, Xiaobo
AU - Pham, Tuan
AU - Sabatini, Bernardo
AU - Wong, Stephen T.C.
N1 - Copyright:
Copyright 2009 Elsevier B.V., All rights reserved.
PY - 2009
Y1 - 2009
N2 - In this brief paper we present an overview of the TSC-mTOR pathway and its importance in neurodegenerative disease (ND). We illustrate the influence of ND on dendritic spine morphology. Then we discuss some details of functional gene networks (FGN) and use this information to propose an image driven systems biology approach for the construction of a FGN for ND. We conclude on its importance and the prospective outcome of our study.
AB - In this brief paper we present an overview of the TSC-mTOR pathway and its importance in neurodegenerative disease (ND). We illustrate the influence of ND on dendritic spine morphology. Then we discuss some details of functional gene networks (FGN) and use this information to propose an image driven systems biology approach for the construction of a FGN for ND. We conclude on its importance and the prospective outcome of our study.
UR - http://www.scopus.com/inward/record.url?scp=67650693023&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=67650693023&partnerID=8YFLogxK
U2 - 10.1109/LISSA.2009.4906703
DO - 10.1109/LISSA.2009.4906703
M3 - Conference contribution
AN - SCOPUS:67650693023
SN - 9781424442935
T3 - 2009 IEEE/NIH Life Science Systems and Applications Workshop, LiSSA 2009
SP - 36
EP - 39
BT - 2009 IEEE/NIH Life Science Systems and Applications Workshop, LiSSA 2009
T2 - 2009 IEEE/NIH Life Science Systems and Applications Workshop, LiSSA 2009
Y2 - 9 April 2009 through 10 April 2009
ER -