An angiographic and histologic study of cocaine-induced chest pain

Pirzada A. Majid, Bharat Patel, Han Seob Kim, Janice L. Zimmerman, R. Phillip Dellinger

Research output: Contribution to journalArticlepeer-review

41 Scopus citations


Chest pain is not an uncommon symptom in patients who abuse cocaine. A small number also develop acute myocardial infarction.1,2 Most, however, show electrocardiographic ST-segment or T-wave abnormalities as the only objective evidence of myocardial ischemia. Coronary artery spasm has been popularly invoked as the possible cause for chest pain.3,4 However, evidence for spasm is largely circumstantial at present. An alternative source of pain may be myocarditis,5 which has been demonstrated in some patients dying of cocaine abuse.6,7.

Original languageEnglish (US)
Pages (from-to)812-814
Number of pages3
JournalThe American Journal of Cardiology
Issue number11
StatePublished - Mar 15 1990

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine


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