Amyotrophic lateral sclerosis with positive anti-acetylcholine receptor antibodies. case report and review of the literature

Raja Mehanna, Eddie Lee Patton, Jr., Cecile L. Phan, Yadollah Harati

Research output: Contribution to journalReview article

16 Scopus citations

Abstract

Myasthenia gravis is a nerve-muscle junction disease, for which the most specific test is an increase in the anti-acetylcholine receptor antibodies (anti-AChR-Abs) titer. Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease affecting both upper and lower motor neurons. Positive AChR-Ab in patients with pure ALS are exceedingly rare. We report the case of a patient with confirmed ALS and very high levels of AChR-Ab and review the literature on this topic.

Original languageEnglish (US)
Pages (from-to)82-85
Number of pages4
JournalJournal of Clinical Neuromuscular Disease
Volume14
Issue number2
DOIs
StatePublished - Dec 1 2012

Keywords

  • acetylcholine receptor antibodies
  • amyotrophic lateral sclerosis
  • myasthenia gravis

ASJC Scopus subject areas

  • Neurology
  • Clinical Neurology

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