@article{36b06138e6934b2aa184616e706f45db,
title = "Aligned microcontact printing of micrometer-scale poly-L-lysine structures for controlled growth of cultured neurons on planar microelectrode arrays",
abstract = "We describe a method for producing high-resolution chemical patterns on surfaces to control the attachment and growth of cultured neurons. Microcontact printing has been extended to allow the printing of μm-scale protein lines aligned to an underlying pattern of planar microelectrodes. Poly-L-lysine (PL) lines have been printed on the electrode array for electrical studies on cultured neural networks. Rat hippocampal neurons showed a high degree of attachment selectivity to the PL and produced neurites that faithfully grew onto the electrode recording sites.",
keywords = "Hippocampal neuron culture, Microcontact printing (μCP), Patterned protein, Planar microelectrode",
author = "James, {C. D.} and R. Davis and M. Meyer and A. Turner and S. Turner and G. Withers and L. Kam and G. Banker and H. Craighead and M. Isaacson and J. Turner and W. Shain",
note = "Funding Information: Manuscript received November 6, 1998; revised August 17, 1999. This work was supported in part by grants from the National Institutes of Health (NIH) and the Defense Advanced Research Projects Agency (DARPA). The work of C. D. James was supported by a fellowship from the National Science Foundation. Asterisk indicates corresponding author. *C. D. James is with the School of Applied and Engineering Physics, Cornell University, Ithaca, NY 14853 USA.",
year = "2000",
doi = "10.1109/10.817614",
language = "English (US)",
volume = "47",
pages = "17--21",
journal = "IEEE Transactions on Biomedical Engineering",
issn = "0018-9294",
publisher = "Institute of Electrical and Electronics Engineers Inc.",
number = "1",
}