Alcohol and sex

C. D. Johnson, Keith O. Reeves, D. Jackson

Research output: Contribution to journalArticlepeer-review

1 Scopus citations


The theory that alcohol causes liver dysfunction, which then causes feminization, is false. Alcohol is a primary gonadotoxin, and in acute and chronic consumers of alcohol it affects both the reproductive and the endocrine compartments of the testes. Acetaldehyde, the first degradation product of alcohol, is highly toxic and alters the testicular redox potential. Hypogonadism is common in alcoholic men and occurs independently of liver disease. Alcohol produces primary gonadal failure and may have an effect on the hypothalamic-pituitary axis.

Original languageEnglish (US)
Pages (from-to)93-97
Number of pages5
JournalHeart and Lung: Journal of Acute and Critical Care
Issue number1
StatePublished - Jan 1 1983

ASJC Scopus subject areas

  • Pulmonary and Respiratory Medicine
  • Critical Care and Intensive Care Medicine
  • Cardiology and Cardiovascular Medicine


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