Air pollution: A culprit of lung cancer

Yueguang Xue, Liuxiang Wang, Yiming Zhang, Yuliang Zhao, Ying Liu

Research output: Contribution to journalReview articlepeer-review

79 Scopus citations

Abstract

Air pollution is a global health problem, especially in the context of rapid economic development and the expansion of urbanization. Herein, we discuss the harmful effects of outdoor and indoor pollution on the lungs. Ambient particulate matters (PMs) from industrial and vehicle exhausts is associated with lung cancer. Workers exposed to asbestos, polycyclic aromatic hydrocarbons (PAHs), and toxic metals are also likely to develop lung cancer. Indoors, cooking fumes, second-hand smoke, and radioactive products from house decoration materials play roles in the development of lung cancer. Bacteria and viruses can also be detrimental to health and are important risk factors in lung inflammation and cancer. Specific effects of lung cancer caused by air pollution are discussed in detail, including inflammation, DNA damage, and epigenetic regulation. In addition, advanced materials for personal protection, as well as the current government policies to prevent air pollution, are summarized. This review provides a basis for future research on the relationship between lung cancer and air pollution.

Original languageEnglish (US)
Article number128937
JournalJournal of Hazardous Materials
Volume434
DOIs
StatePublished - Jul 15 2022

Keywords

  • Air pollution
  • Health
  • Lung cancer
  • Pathogenesis

ASJC Scopus subject areas

  • Environmental Engineering
  • Environmental Chemistry
  • Waste Management and Disposal
  • Pollution
  • Health, Toxicology and Mutagenesis

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