Aging studies in drosophila melanogaster

Yaning Sun, Jason Yolitz, Cecilia Wang, Edward Spangler, Ming Zhan, Sige Zou

Research output: Chapter in Book/Report/Conference proceedingChapter

47 Scopus citations


Drosophila is a genetically tractable system ideal for investigating the mechanisms of aging and developing interventions for promoting healthy aging. Here we describe methods commonly used in Drosophila aging research. These include basic approaches for preparation of diets and measurements of lifespan, food intake, and reproductive output. We also describe some commonly used assays to measure changes in physiological and behavioral functions of Drosophila in aging, such as stress resistance and locomotor activity.

Original languageEnglish (US)
Title of host publicationBiological Aging
Subtitle of host publicationMethods and Protocols
PublisherHumana Press
Number of pages17
ISBN (Print)9781627035552
StatePublished - 2013

Publication series

NameMethods in Molecular Biology
ISSN (Print)1064-3745


  • Aging
  • Drosophila melanogaster
  • Lifespan
  • Locomotor activity
  • Mitochondrial function
  • Oxidative stress
  • Reproduction
  • Starvation

ASJC Scopus subject areas

  • Molecular Biology
  • Genetics


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