Aging studies in drosophila melanogaster

Yaning Sun; Jason Yolitz; Cecilia Wang; Edward Spangler; Ming Zhan; Sige Zou

doi:10.1007/978-1-62703-556-9_7

Aging studies in drosophila melanogaster

Yaning Sun, Jason Yolitz, Cecilia Wang, Edward Spangler, Ming Zhan, Sige Zou

Academic Institute

Research output: Chapter in Book/Report/Conference proceeding › Chapter

50 Scopus citations

Abstract

Drosophila is a genetically tractable system ideal for investigating the mechanisms of aging and developing interventions for promoting healthy aging. Here we describe methods commonly used in Drosophila aging research. These include basic approaches for preparation of diets and measurements of lifespan, food intake, and reproductive output. We also describe some commonly used assays to measure changes in physiological and behavioral functions of Drosophila in aging, such as stress resistance and locomotor activity.

Original language	English (US)
Title of host publication	Biological Aging
Subtitle of host publication	Methods and Protocols
Publisher	Humana Press
Pages	77-93
Number of pages	17
ISBN (Print)	9781627035552
DOIs	https://doi.org/10.1007/978-1-62703-556-9_7
State	Published - 2013

Publication series

Name	Methods in Molecular Biology
Volume	1048
ISSN (Print)	1064-3745

Keywords

Aging
Drosophila melanogaster
Lifespan
Locomotor activity
Mitochondrial function
Oxidative stress
Reproduction
Starvation

ASJC Scopus subject areas

Molecular Biology
Genetics

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10.1007/978-1-62703-556-9_7

Cite this

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AU - Sun, Yaning

AU - Yolitz, Jason

AU - Wang, Cecilia

AU - Spangler, Edward

AU - Zhan, Ming

AU - Zou, Sige

PY - 2013

Y1 - 2013

N2 - Drosophila is a genetically tractable system ideal for investigating the mechanisms of aging and developing interventions for promoting healthy aging. Here we describe methods commonly used in Drosophila aging research. These include basic approaches for preparation of diets and measurements of lifespan, food intake, and reproductive output. We also describe some commonly used assays to measure changes in physiological and behavioral functions of Drosophila in aging, such as stress resistance and locomotor activity.

AB - Drosophila is a genetically tractable system ideal for investigating the mechanisms of aging and developing interventions for promoting healthy aging. Here we describe methods commonly used in Drosophila aging research. These include basic approaches for preparation of diets and measurements of lifespan, food intake, and reproductive output. We also describe some commonly used assays to measure changes in physiological and behavioral functions of Drosophila in aging, such as stress resistance and locomotor activity.

KW - Aging

KW - Drosophila melanogaster

KW - Lifespan

KW - Locomotor activity

KW - Mitochondrial function

KW - Oxidative stress

KW - Reproduction

KW - Starvation

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SP - 77

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ER -

Aging studies in drosophila melanogaster

Abstract

Publication series

Keywords

ASJC Scopus subject areas

Access to Document

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