Advising patients about breast implant associated anaplastic large cell lymphoma

Christopher S. Parham, Summer E. Hanson, Charles E. Butler, M. Bradley Calobrace, Raylene Hollrah, Terri Macgregor, Mark W. Clemens

Research output: Contribution to journalReview articlepeer-review

1 Scopus citations

Abstract

Abstract: The United States Food and Drug Administration (FDA) recently recognized the necessity for improved patient education and public awareness of breast implant-associated anaplastic large cell lymphoma (BIA-ALCL). BIA-ALCL is an uncommon T-cell lymphoma that can arise years after placement of a textured breast implant or tissue expander. Patients and providers would greatly benefit from a broader awareness of BIA-ALCL and how it presents with both common and rare symptoms. Disease awareness can be improved with specific steps moving forward. This includes improved counseling about annual recommendations from the FDA, standard of care guidelines, current estimates of disease prevalence, and manufacturer-specific risk for developing the malignancy. Informed consent for implant-based breast surgery should include a discussion of BIA-ALCL, symptoms, inherent risks and alternatives. Consideration should be given for reasonable efforts to retroactively contact patients with textured implants to inform them of recent regulatory actions as well as the risk of developing the disease and the signs and symptoms to watch for. Where risk can be reduced, all steps should be taken to ensure patient safety. In keeping with our commitment to patient safety, the strategies moving forward for implant-based breast surgery should be marked by patient awareness, physician vigilance, and defined by evidence-based diagnosis and treatment.

Original languageEnglish (US)
Pages (from-to)417-429
Number of pages13
JournalGland Surgery
Volume10
Issue number1
DOIs
StatePublished - Jan 2021

Keywords

  • Breast implants
  • breast implant associated
  • breast implant-associated anaplastic large cell lymphoma (BIA-ALCL)
  • device safety
  • informed consent

ASJC Scopus subject areas

  • Surgery

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