TY - JOUR
T1 - Advanced material technologies for space and terrestrial medicine
AU - Chua, Corrine Ying Xuan
AU - Jimenez, Miguel
AU - Mozneb, Maedeh
AU - Traverso, Giovanni
AU - Lugo, Ray
AU - Sharma, Arun
AU - Svendsen, Clive N.
AU - Wagner, William R.
AU - Langer, Robert
AU - Grattoni, Alessandro
N1 - Publisher Copyright:
© Springer Nature Limited 2024.
PY - 2024/11
Y1 - 2024/11
N2 - The medical risks of spaceflight are amplified as humans venture into longer-duration and greater-distance deep space voyages. During space missions, astronauts face the extremes of known health hazards, such as cosmic radiation and microgravity, as well as threats of the as-yet-unknown. For these missions to be productive and successful, ensuring the astronauts’ safety and well-being is of foremost priority, and this could be achieved through innovations in space medicine. This Perspective explores the use of material technologies for delivery of space medicine in the context of health maintenance and preventive care, as well as treatment for non-emergency and emergency needs. We highlight innovative drug delivery systems, living pharmacies, regenerative medicine, and 3D printing and bioprinting approaches for health-care provision, and we share our vision on their potential applications in space. Finally, we discuss the benefits of space medicine research and its implications for advancing terrestrial health care.
AB - The medical risks of spaceflight are amplified as humans venture into longer-duration and greater-distance deep space voyages. During space missions, astronauts face the extremes of known health hazards, such as cosmic radiation and microgravity, as well as threats of the as-yet-unknown. For these missions to be productive and successful, ensuring the astronauts’ safety and well-being is of foremost priority, and this could be achieved through innovations in space medicine. This Perspective explores the use of material technologies for delivery of space medicine in the context of health maintenance and preventive care, as well as treatment for non-emergency and emergency needs. We highlight innovative drug delivery systems, living pharmacies, regenerative medicine, and 3D printing and bioprinting approaches for health-care provision, and we share our vision on their potential applications in space. Finally, we discuss the benefits of space medicine research and its implications for advancing terrestrial health care.
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U2 - 10.1038/s41578-024-00691-0
DO - 10.1038/s41578-024-00691-0
M3 - Article
AN - SCOPUS:85195208078
SN - 2058-8437
VL - 9
SP - 808
EP - 821
JO - Nature Reviews Materials
JF - Nature Reviews Materials
IS - 11
ER -