Adult-to-adult living-donor liver transplantation: A critical analysis

J. F. Renz, R. W. Busuttil

Research output: Contribution to journalArticlepeer-review

81 Scopus citations

Abstract

Adult-to-adult living-donor liver transplantation is the most recent achievement in the evolution of strategies to increase donor organ supply. Justification of the procedure has evolved from increased organ-waiting times, wait-list morbidity and mortality of adult transplant candidates. Successful application of adult-to-adult living-donor liver transplantation mandates unique surgical, medical, and donor considerations as these procedures predispose to unique complications resulting from anatomic variations, technical considerations, and the transplantation of "partial" grafts. Additionally, because the magnitude of the donor operation is greater and potentially fraught with serious short and long term morbidity and possibly mortality, the utilization of living-donors for adult liver transplantation raises bio-ethical concerns heretofore not encountered. This review explores the current state of adult-to-adult living-donor liver transplantation.

Original languageEnglish (US)
Pages (from-to)411-424
Number of pages14
JournalSeminars in Liver Disease
Volume20
Issue number4
DOIs
StatePublished - 2000

Keywords

  • Adult living-donor liver transplantation
  • Liver
  • Liver transplant surgery
  • Organ donation

ASJC Scopus subject areas

  • Hepatology

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