Adipose-derived cellular and cell-derived regenerative therapies in dermatology and aesthetic rejuvenation

Annie Suh; Anthony Pham; Mikel Jean Cress; Thais Pincelli; Sarvam P. TerKonda; Alison J. Bruce; Abba C. Zubair; Joy Wolfram; Shane A. Shapiro

doi:10.1016/j.arr.2019.100933

Adipose-derived cellular and cell-derived regenerative therapies in dermatology and aesthetic rejuvenation

Annie Suh, Anthony Pham, Mikel Jean Cress, Thais Pincelli, Sarvam P. TerKonda, Alison J. Bruce, Abba C. Zubair, Joy Wolfram, Shane A. Shapiro

Houston Methodist

Research output: Contribution to journal › Review article › peer-review

92 Scopus citations

Abstract

Cellular and cell-derived components of adipose-derived tissue for the purposes of dermatologic and aesthetic rejuvenation applications have become increasingly studied and integrated into clinical practice. These components include micro-fragmented fat (nanofat), the stromal vascular fraction (SVF), adipose-derived mesenchymal stem cells (ASC), and extracellular vesicles (EVs), which have all shown capability to repair, regenerate, and rejuvenate surrounding tissue. Various aesthetic applications including hair growth, scar reduction, skin ischemia-reperfusion recovery, and facial rejuvenation are reviewed. In particular, results from preclinical and clinical studies are discussed, with a focus on clarification of nomenclature.

Original language	English (US)
Article number	100933
Journal	Ageing Research Reviews
Volume	54
DOIs	https://doi.org/10.1016/j.arr.2019.100933
State	Published - Sep 2019

Keywords

Adipose
Extracellular vesicles
Mesenchymal stem cells
Nanofat
Regenerative medicine
Stromal vascular fraction

ASJC Scopus subject areas

Biotechnology
Biochemistry
Aging
Molecular Biology
Neurology

Access to Document

10.1016/j.arr.2019.100933

Cite this

@article{011c44b5ffb8433ca7037ced44fb6321,

title = "Adipose-derived cellular and cell-derived regenerative therapies in dermatology and aesthetic rejuvenation",

abstract = "Cellular and cell-derived components of adipose-derived tissue for the purposes of dermatologic and aesthetic rejuvenation applications have become increasingly studied and integrated into clinical practice. These components include micro-fragmented fat (nanofat), the stromal vascular fraction (SVF), adipose-derived mesenchymal stem cells (ASC), and extracellular vesicles (EVs), which have all shown capability to repair, regenerate, and rejuvenate surrounding tissue. Various aesthetic applications including hair growth, scar reduction, skin ischemia-reperfusion recovery, and facial rejuvenation are reviewed. In particular, results from preclinical and clinical studies are discussed, with a focus on clarification of nomenclature.",

keywords = "Adipose, Extracellular vesicles, Mesenchymal stem cells, Nanofat, Regenerative medicine, Stromal vascular fraction",

author = "Annie Suh and Anthony Pham and Cress, \{Mikel Jean\} and Thais Pincelli and TerKonda, \{Sarvam P.\} and Bruce, \{Alison J.\} and Zubair, \{Abba C.\} and Joy Wolfram and Shapiro, \{Shane A.\}",

note = "Publisher Copyright: {\textcopyright} 2019 Elsevier B.V.",

year = "2019",

month = sep,

doi = "10.1016/j.arr.2019.100933",

language = "English (US)",

volume = "54",

journal = "Ageing Research Reviews",

issn = "1568-1637",

publisher = "Elsevier Ireland Ltd",

}

TY - JOUR

T1 - Adipose-derived cellular and cell-derived regenerative therapies in dermatology and aesthetic rejuvenation

AU - Suh, Annie

AU - Pham, Anthony

AU - Cress, Mikel Jean

AU - Pincelli, Thais

AU - TerKonda, Sarvam P.

AU - Bruce, Alison J.

AU - Zubair, Abba C.

AU - Wolfram, Joy

AU - Shapiro, Shane A.

PY - 2019/9

Y1 - 2019/9

N2 - Cellular and cell-derived components of adipose-derived tissue for the purposes of dermatologic and aesthetic rejuvenation applications have become increasingly studied and integrated into clinical practice. These components include micro-fragmented fat (nanofat), the stromal vascular fraction (SVF), adipose-derived mesenchymal stem cells (ASC), and extracellular vesicles (EVs), which have all shown capability to repair, regenerate, and rejuvenate surrounding tissue. Various aesthetic applications including hair growth, scar reduction, skin ischemia-reperfusion recovery, and facial rejuvenation are reviewed. In particular, results from preclinical and clinical studies are discussed, with a focus on clarification of nomenclature.

AB - Cellular and cell-derived components of adipose-derived tissue for the purposes of dermatologic and aesthetic rejuvenation applications have become increasingly studied and integrated into clinical practice. These components include micro-fragmented fat (nanofat), the stromal vascular fraction (SVF), adipose-derived mesenchymal stem cells (ASC), and extracellular vesicles (EVs), which have all shown capability to repair, regenerate, and rejuvenate surrounding tissue. Various aesthetic applications including hair growth, scar reduction, skin ischemia-reperfusion recovery, and facial rejuvenation are reviewed. In particular, results from preclinical and clinical studies are discussed, with a focus on clarification of nomenclature.

KW - Adipose

KW - Extracellular vesicles

KW - Mesenchymal stem cells

KW - Nanofat

KW - Regenerative medicine

KW - Stromal vascular fraction

UR - https://www.scopus.com/pages/publications/85067850008

UR - https://www.scopus.com/inward/citedby.url?scp=85067850008&partnerID=8YFLogxK

U2 - 10.1016/j.arr.2019.100933

DO - 10.1016/j.arr.2019.100933

M3 - Review article

C2 - 31247326

AN - SCOPUS:85067850008

SN - 1568-1637

VL - 54

JO - Ageing Research Reviews

JF - Ageing Research Reviews

M1 - 100933

ER -

Adipose-derived cellular and cell-derived regenerative therapies in dermatology and aesthetic rejuvenation

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this