Adipose-derived cellular and cell-derived regenerative therapies in dermatology and aesthetic rejuvenation

Annie Suh, Anthony Pham, Mikel Jean Cress, Thais Pincelli, Sarvam P. TerKonda, Alison J. Bruce, Abba C. Zubair, Joy Wolfram, Shane A. Shapiro

Research output: Contribution to journalReview articlepeer-review

70 Scopus citations


Cellular and cell-derived components of adipose-derived tissue for the purposes of dermatologic and aesthetic rejuvenation applications have become increasingly studied and integrated into clinical practice. These components include micro-fragmented fat (nanofat), the stromal vascular fraction (SVF), adipose-derived mesenchymal stem cells (ASC), and extracellular vesicles (EVs), which have all shown capability to repair, regenerate, and rejuvenate surrounding tissue. Various aesthetic applications including hair growth, scar reduction, skin ischemia-reperfusion recovery, and facial rejuvenation are reviewed. In particular, results from preclinical and clinical studies are discussed, with a focus on clarification of nomenclature.

Original languageEnglish (US)
Article number100933
JournalAgeing Research Reviews
StatePublished - Sep 2019


  • Adipose
  • Extracellular vesicles
  • Mesenchymal stem cells
  • Nanofat
  • Regenerative medicine
  • Stromal vascular fraction

ASJC Scopus subject areas

  • Biotechnology
  • Biochemistry
  • Aging
  • Molecular Biology
  • Neurology


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