Adenoid cystic carcinoma of the minor salivary glands: A retrospective series of 29 cases and review of the literature

Jonathan Shum, Ioannis Chatzistefanou, Mohammed Qaisi, Joshua E. Lubek, Robert A. Ord

Research output: Contribution to journalReview article

12 Scopus citations

Abstract

Objective Approximately 78% of minor salivary gland tumors are malignant, of which adenoid cystic carcinoma (ACC) represents 15% in our series. ACC is an uncommon tumor characterized by slow growth and a high potential for recurrence. This series of 29 consecutive patients examines clincopathologic features, management, and survival outcomes. Materials and Methods This study is a retrospective chart review of 29 patients with ACC of the minor salivary glands in a period of 23 years (1989 and 2012). Results The mean age was 61.2 years (16-89 years), with no gender predilection. The majority occurred in the palate/maxilla (66%) and initial presentation was stage IV. Mean follow-up was 42.6 months. Recurrence rate was 10% local, 14% distant over the observation period. Conclusions The palate/maxilla is the preferred location for occurrence, and initial presentation at stage IV is common. Postoperative radiation remains a common strategy to prevent local recurrence in lesions with adverse features.

Original languageEnglish (US)
Pages (from-to)210-214
Number of pages5
JournalOral Surgery, Oral Medicine, Oral Pathology and Oral Radiology
Volume121
Issue number3
DOIs
StatePublished - Mar 1 2016

ASJC Scopus subject areas

  • Surgery
  • Oral Surgery
  • Pathology and Forensic Medicine
  • Dentistry (miscellaneous)
  • Radiology Nuclear Medicine and imaging

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