Acute myocardial infarction: Tissue characterization with T1 ρ-weighted MR imaging - Initial experience

Raja Muthupillai; Scott D. Flamm; James M. Wilson; Roderic I. Pettigrew; W. Thomas Dixon

doi:10.1148/radiol.2322030334

Acute myocardial infarction: Tissue characterization with T1 _ρ-weighted MR imaging - Initial experience

Raja Muthupillai, Scott D. Flamm, James M. Wilson, Roderic I. Pettigrew, W. Thomas Dixon

Research output: Contribution to journal › Article › peer-review

53 Scopus citations

Abstract

Acute myocardial injury was evaluated in 21 patients by using a contrast material-enhanced T1_ρ-weighted cine turbo field-echo magnetic resonance (MR) imaging sequence and a delayed-enhancement sequence. In 12 of 21 patients, conventional T1-weighted contrast-enhanced cine turbo field-echo MR images were also collected for direct comparison with T1_ρ- weighted images. Delayed-enhancement technique distinctly characterized irreversible injury (percentage enhancement, 588% ± 344). With T1 _ρ weighting, percentage enhancement of irreversibly injured myocardium was 68% ± 41, compared with 23% ± 24 without T1 _ρ weighting (P < .006). The addition of T1_ρ weighting to contrast-enhanced cine turbo field-echo MR sequences may offer a new contrast enhancement mechanism for characterization of acutely infarcted myocardium.

Original language	English (US)
Pages (from-to)	606-610
Number of pages	5
Journal	Radiology
Volume	232
Issue number	2
DOIs	https://doi.org/10.1148/radiol.2322030334
State	Published - Aug 2004

Keywords

Magnetic resonance (MR), cine study
Magnetic resonance (MR), tissue characterization
Myocardium, MR
Myocardium, infarction

ASJC Scopus subject areas

Radiology Nuclear Medicine and imaging

Access to Document

10.1148/radiol.2322030334

Cite this

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title = "Acute myocardial infarction: Tissue characterization with T1 ρ-weighted MR imaging - Initial experience",

abstract = "Acute myocardial injury was evaluated in 21 patients by using a contrast material-enhanced T1ρ-weighted cine turbo field-echo magnetic resonance (MR) imaging sequence and a delayed-enhancement sequence. In 12 of 21 patients, conventional T1-weighted contrast-enhanced cine turbo field-echo MR images were also collected for direct comparison with T1ρ- weighted images. Delayed-enhancement technique distinctly characterized irreversible injury (percentage enhancement, 588% ± 344). With T1 ρ weighting, percentage enhancement of irreversibly injured myocardium was 68% ± 41, compared with 23% ± 24 without T1 ρ weighting (P < .006). The addition of T1ρ weighting to contrast-enhanced cine turbo field-echo MR sequences may offer a new contrast enhancement mechanism for characterization of acutely infarcted myocardium.",

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T2 - Tissue characterization with T1 ρ-weighted MR imaging - Initial experience

AU - Muthupillai, Raja

AU - Flamm, Scott D.

AU - Wilson, James M.

AU - Pettigrew, Roderic I.

AU - Dixon, W. Thomas

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