Acute myocardial infarction: Tissue characterization with T1 ρ-weighted MR imaging - Initial experience

Raja Muthupillai, Scott D. Flamm, James M. Wilson, Roderic I. Pettigrew, W. Thomas Dixon

Research output: Contribution to journalArticle

37 Scopus citations


Acute myocardial injury was evaluated in 21 patients by using a contrast material-enhanced T1ρ-weighted cine turbo field-echo magnetic resonance (MR) imaging sequence and a delayed-enhancement sequence. In 12 of 21 patients, conventional T1-weighted contrast-enhanced cine turbo field-echo MR images were also collected for direct comparison with T1ρ- weighted images. Delayed-enhancement technique distinctly characterized irreversible injury (percentage enhancement, 588% ± 344). With T1 ρ weighting, percentage enhancement of irreversibly injured myocardium was 68% ± 41, compared with 23% ± 24 without T1 ρ weighting (P < .006). The addition of T1ρ weighting to contrast-enhanced cine turbo field-echo MR sequences may offer a new contrast enhancement mechanism for characterization of acutely infarcted myocardium.

Original languageEnglish (US)
Pages (from-to)606-610
Number of pages5
Issue number2
StatePublished - Aug 1 2004


  • Magnetic resonance (MR), cine study
  • Magnetic resonance (MR), tissue characterization
  • Myocardium, MR
  • Myocardium, infarction

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

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