Acceptability of interferon-gamma release assays among healthcare workers who receive routine employee tuberculosis testing

Yael Hirsch-Moverman; Kirsten Wall; Paul Weinfurter; Elizabeth Munk; Joyce Ann Moran; Allison Maiuris; Amera Khan; Nichlas DeLuca; TB Epidemiologic Studies Consortium

doi:10.1179/2049396713Y.0000000038

Acceptability of interferon-gamma release assays among healthcare workers who receive routine employee tuberculosis testing

Yael Hirsch-Moverman, Kirsten Wall, Paul Weinfurter, Elizabeth Munk, Joyce Ann Moran, Allison Maiuris, Amera Khan, Nichlas DeLuca, TB Epidemiologic Studies Consortium

Research output: Contribution to journal › Article › peer-review

3 Scopus citations

Abstract

BACKGROUND: Healthcare workers (HCWs) undergo annual testing for latent tuberculosis infection (LTBI).

OBJECTIVE: Compare acceptability of tuberculin skin test (TST) and interferon-gamma release assay (IGRA) among HCWs.

METHODS: HCWs at four medical centers in the US were administered an acceptability questionnaire including a brief objective description of both tests and eliciting attitudes regarding TST and IGRAs, confidence in results, and likelihood of taking LTBI treatment.

RESULTS: Of 406 participants, 75% had never heard of IGRAs. IGRAs were preferred to TST. Belief in accuracy of hypothetical positive results of TST or IGRA and willingness to accept LTBI treatment were similar across tests. When presented with hypothetical discordant results, HCWs expressed more confidence in IGRAs. Perceived accuracy of results was the most important factor in test preferences.

CONCLUSIONS: Although HCWs preferred and indicated more confidence in IGRAs, the likelihood that HCWs would believe LTBI diagnosis and initiate treatment based on positive results was similar for TST and IGRAs.

Original language	English (US)
Pages (from-to)	319-24
Number of pages	6
Journal	International journal of occupational and environmental health
Volume	19
Issue number	4
DOIs	https://doi.org/10.1179/2049396713Y.0000000038
State	Published - Mar 4 2014
Externally published	Yes

Keywords

Adult
Attitude of Health Personnel
Female
Health Personnel
Humans
Interferon-gamma Release Tests
Latent Tuberculosis
Male
Middle Aged
Patient Preference
Sensitivity and Specificity
Tuberculin Test
United States

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10.1179/2049396713Y.0000000038

Cite this

Hirsch-Moverman, Y., Wall, K., Weinfurter, P., Munk, E., Moran, J. A., Maiuris, A., Khan, A., DeLuca, N., & TB Epidemiologic Studies Consortium (2014). Acceptability of interferon-gamma release assays among healthcare workers who receive routine employee tuberculosis testing. International journal of occupational and environmental health, 19(4), 319-24. https://doi.org/10.1179/2049396713Y.0000000038

Hirsch-Moverman, Y, Wall, K, Weinfurter, P, Munk, E, Moran, JA, Maiuris, A, Khan, A, DeLuca, N & TB Epidemiologic Studies Consortium 2014, 'Acceptability of interferon-gamma release assays among healthcare workers who receive routine employee tuberculosis testing', International journal of occupational and environmental health, vol. 19, no. 4, pp. 319-24. https://doi.org/10.1179/2049396713Y.0000000038

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title = "Acceptability of interferon-gamma release assays among healthcare workers who receive routine employee tuberculosis testing",

abstract = "BACKGROUND: Healthcare workers (HCWs) undergo annual testing for latent tuberculosis infection (LTBI).OBJECTIVE: Compare acceptability of tuberculin skin test (TST) and interferon-gamma release assay (IGRA) among HCWs.METHODS: HCWs at four medical centers in the US were administered an acceptability questionnaire including a brief objective description of both tests and eliciting attitudes regarding TST and IGRAs, confidence in results, and likelihood of taking LTBI treatment.RESULTS: Of 406 participants, 75% had never heard of IGRAs. IGRAs were preferred to TST. Belief in accuracy of hypothetical positive results of TST or IGRA and willingness to accept LTBI treatment were similar across tests. When presented with hypothetical discordant results, HCWs expressed more confidence in IGRAs. Perceived accuracy of results was the most important factor in test preferences.CONCLUSIONS: Although HCWs preferred and indicated more confidence in IGRAs, the likelihood that HCWs would believe LTBI diagnosis and initiate treatment based on positive results was similar for TST and IGRAs.",

keywords = "Adult, Attitude of Health Personnel, Female, Health Personnel, Humans, Interferon-gamma Release Tests, Latent Tuberculosis, Male, Middle Aged, Patient Preference, Sensitivity and Specificity, Tuberculin Test, United States",

author = "Yael Hirsch-Moverman and Kirsten Wall and Paul Weinfurter and Elizabeth Munk and Moran, {Joyce Ann} and Allison Maiuris and Amera Khan and Nichlas DeLuca and {TB Epidemiologic Studies Consortium}",

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doi = "10.1179/2049396713Y.0000000038",

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AU - Wall, Kirsten

AU - Weinfurter, Paul

AU - Munk, Elizabeth

AU - Moran, Joyce Ann

AU - Maiuris, Allison

AU - Khan, Amera

AU - DeLuca, Nichlas

AU - TB Epidemiologic Studies Consortium

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N2 - BACKGROUND: Healthcare workers (HCWs) undergo annual testing for latent tuberculosis infection (LTBI).OBJECTIVE: Compare acceptability of tuberculin skin test (TST) and interferon-gamma release assay (IGRA) among HCWs.METHODS: HCWs at four medical centers in the US were administered an acceptability questionnaire including a brief objective description of both tests and eliciting attitudes regarding TST and IGRAs, confidence in results, and likelihood of taking LTBI treatment.RESULTS: Of 406 participants, 75% had never heard of IGRAs. IGRAs were preferred to TST. Belief in accuracy of hypothetical positive results of TST or IGRA and willingness to accept LTBI treatment were similar across tests. When presented with hypothetical discordant results, HCWs expressed more confidence in IGRAs. Perceived accuracy of results was the most important factor in test preferences.CONCLUSIONS: Although HCWs preferred and indicated more confidence in IGRAs, the likelihood that HCWs would believe LTBI diagnosis and initiate treatment based on positive results was similar for TST and IGRAs.

AB - BACKGROUND: Healthcare workers (HCWs) undergo annual testing for latent tuberculosis infection (LTBI).OBJECTIVE: Compare acceptability of tuberculin skin test (TST) and interferon-gamma release assay (IGRA) among HCWs.METHODS: HCWs at four medical centers in the US were administered an acceptability questionnaire including a brief objective description of both tests and eliciting attitudes regarding TST and IGRAs, confidence in results, and likelihood of taking LTBI treatment.RESULTS: Of 406 participants, 75% had never heard of IGRAs. IGRAs were preferred to TST. Belief in accuracy of hypothetical positive results of TST or IGRA and willingness to accept LTBI treatment were similar across tests. When presented with hypothetical discordant results, HCWs expressed more confidence in IGRAs. Perceived accuracy of results was the most important factor in test preferences.CONCLUSIONS: Although HCWs preferred and indicated more confidence in IGRAs, the likelihood that HCWs would believe LTBI diagnosis and initiate treatment based on positive results was similar for TST and IGRAs.

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KW - Attitude of Health Personnel

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KW - Health Personnel

KW - Humans

KW - Interferon-gamma Release Tests

KW - Latent Tuberculosis

KW - Male

KW - Middle Aged

KW - Patient Preference

KW - Sensitivity and Specificity

KW - Tuberculin Test

KW - United States

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JO - International journal of occupational and environmental health

JF - International journal of occupational and environmental health

SN - 1077-3525

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ER -

Acceptability of interferon-gamma release assays among healthcare workers who receive routine employee tuberculosis testing

Abstract

Keywords

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