Absent factor II in systemic lupus erythematosus. Immunologic studies and response to corticosteroid therapy

Ethan Natelson, Gerald S. Cyprus, Robert A. Hettig

Research output: Contribution to journalArticle

28 Scopus citations

Abstract

This report describes a patient with active systemic lupus erythematosus (SLE) who evidenced severe bleeding consequent to a profound and isolated reduction in plasma factor II (prothrombin) activity. Absence of the factor is documented by immunologic means and its return after corticosteroid therapy is demonstrated. The authors recommend inclusion of this acquired coagulopathy among other more traditional diagnostic manifestations of SLE.

Original languageEnglish (US)
Pages (from-to)79-82
Number of pages4
JournalArthritis & Rheumatism
Volume19
Issue number1
DOIs
StatePublished - 1976

ASJC Scopus subject areas

  • Immunology and Allergy
  • Rheumatology
  • Immunology
  • Pharmacology (medical)

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