ABO matching in liver transplantation

Y. Iwaki; T. Ashizawa; D. Cook; H. Furui; H. Takiff; S. Mcdiarmid; P. I. Terasaki; J. O. Colonna; J. Brems; R. W. Busuttil

ABO matching in liver transplantation

Y. Iwaki, T. Ashizawa, D. Cook, H. Furui, H. Takiff, S. Mcdiarmid, P. I. Terasaki, J. O. Colonna, J. Brems, R. W. Busuttil

Research output: Contribution to journal › Article › peer-review

7 Scopus citations

Abstract

This study demonstrates a possible disadvantage of crossing ABO barriers in liver transplantations. In adult recipients, those who received ABO-compatible livers had lower graft survivals if the ABO antigen were not identical. This could be due to the fact that transplanted liver might produce hemoagglutinins against the mismatched recipient's ABO antigens that eventually would damage the transplanted liver. Another possible reason why these pediatric livers provided a higher graft survival rate could be that the pediatric liver cells bear fewer ABO antigens compared to the adult liver cells. Yet before extended studies are completed, ABO-identical grafts should be recommended in adult liver transplantation except in emergency situations.

Original language	English (US)
Pages (from-to)	564-565
Number of pages	2
Journal	Transplantation Proceedings
Volume	20
Issue number	1 SUPPL. 1
State	Published - 1988

ASJC Scopus subject areas

Surgery
Transplantation

Cite this

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title = "ABO matching in liver transplantation",

abstract = "This study demonstrates a possible disadvantage of crossing ABO barriers in liver transplantations. In adult recipients, those who received ABO-compatible livers had lower graft survivals if the ABO antigen were not identical. This could be due to the fact that transplanted liver might produce hemoagglutinins against the mismatched recipient's ABO antigens that eventually would damage the transplanted liver. Another possible reason why these pediatric livers provided a higher graft survival rate could be that the pediatric liver cells bear fewer ABO antigens compared to the adult liver cells. Yet before extended studies are completed, ABO-identical grafts should be recommended in adult liver transplantation except in emergency situations.",

author = "Y. Iwaki and T. Ashizawa and D. Cook and H. Furui and H. Takiff and S. Mcdiarmid and Terasaki, {P. I.} and Colonna, {J. O.} and J. Brems and Busuttil, {R. W.}",

year = "1988",

language = "English (US)",

volume = "20",

pages = "564--565",

journal = "Transplantation Proceedings",

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T1 - ABO matching in liver transplantation

AU - Iwaki, Y.

AU - Ashizawa, T.

AU - Cook, D.

AU - Furui, H.

AU - Takiff, H.

AU - Mcdiarmid, S.

AU - Terasaki, P. I.

AU - Colonna, J. O.

AU - Brems, J.

AU - Busuttil, R. W.

PY - 1988

Y1 - 1988

N2 - This study demonstrates a possible disadvantage of crossing ABO barriers in liver transplantations. In adult recipients, those who received ABO-compatible livers had lower graft survivals if the ABO antigen were not identical. This could be due to the fact that transplanted liver might produce hemoagglutinins against the mismatched recipient's ABO antigens that eventually would damage the transplanted liver. Another possible reason why these pediatric livers provided a higher graft survival rate could be that the pediatric liver cells bear fewer ABO antigens compared to the adult liver cells. Yet before extended studies are completed, ABO-identical grafts should be recommended in adult liver transplantation except in emergency situations.

AB - This study demonstrates a possible disadvantage of crossing ABO barriers in liver transplantations. In adult recipients, those who received ABO-compatible livers had lower graft survivals if the ABO antigen were not identical. This could be due to the fact that transplanted liver might produce hemoagglutinins against the mismatched recipient's ABO antigens that eventually would damage the transplanted liver. Another possible reason why these pediatric livers provided a higher graft survival rate could be that the pediatric liver cells bear fewer ABO antigens compared to the adult liver cells. Yet before extended studies are completed, ABO-identical grafts should be recommended in adult liver transplantation except in emergency situations.

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AN - SCOPUS:0023943621

SN - 0041-1345

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JO - Transplantation Proceedings

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ABO matching in liver transplantation

Abstract

ASJC Scopus subject areas

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