Abnormal multifocal electroretinogram (mfERG) in ethambutol toxicity

Randy H. Kardon; Mary C. Morrisey; Andrew G. Lee

doi:10.1080/08820530600987454

Abnormal multifocal electroretinogram (mfERG) in ethambutol toxicity

Randy H. Kardon, Mary C. Morrisey, Andrew G. Lee

Research output: Contribution to journal › Article › peer-review

24 Scopus citations

Abstract

Objective: To report the abnormal multifocal electroretinogram (mfERG) findings in two cases of presumed ethambutol toxicity. Design: Retrospective observational case series. Participants: Two patients with ethambutol toxicity and visual loss. Testing: Multifocal electroretinography. Main outcome measure: Waveform measurements on multifocal electroretinography. Results: Two patients with bilateral visual loss due to ethambutol toxicity underwent mfERG testing that disclosed both diffuse and central field loss compatible with retinal dysfunction as a contributing mechanism to the visual field loss. Conclusion: Ethambutol toxicity affects not only the optic nerve but probably other retinal elements based upon abnormal mfERG findings.

Original language	English (US)
Pages (from-to)	215-222
Number of pages	8
Journal	Seminars in Ophthalmology
Volume	21
Issue number	4
DOIs	https://doi.org/10.1080/08820530600987454
State	Published - Oct 2006

ASJC Scopus subject areas

Ophthalmology

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10.1080/08820530600987454

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title = "Abnormal multifocal electroretinogram (mfERG) in ethambutol toxicity",

abstract = "Objective: To report the abnormal multifocal electroretinogram (mfERG) findings in two cases of presumed ethambutol toxicity. Design: Retrospective observational case series. Participants: Two patients with ethambutol toxicity and visual loss. Testing: Multifocal electroretinography. Main outcome measure: Waveform measurements on multifocal electroretinography. Results: Two patients with bilateral visual loss due to ethambutol toxicity underwent mfERG testing that disclosed both diffuse and central field loss compatible with retinal dysfunction as a contributing mechanism to the visual field loss. Conclusion: Ethambutol toxicity affects not only the optic nerve but probably other retinal elements based upon abnormal mfERG findings.",

author = "Kardon, {Randy H.} and Morrisey, {Mary C.} and Lee, {Andrew G.}",

note = "Funding Information: This work was supported in part by an unrestricted grant from Research to Prevent Blindness, Inc., N.Y., N.Y. and support from the Veterans Administration through a Merit Grant and from the Rehabilitation Division (Dr. Kardon). Normative data was kindly provided by Christina Gerth, M.D., Ophthal-Hosp for Sick Children, University of Toronto, Toronto, ON. Copyright: Copyright 2008 Elsevier B.V., All rights reserved.",

year = "2006",

month = oct,

doi = "10.1080/08820530600987454",

language = "English (US)",

volume = "21",

pages = "215--222",

journal = "Seminars in Ophthalmology",

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T1 - Abnormal multifocal electroretinogram (mfERG) in ethambutol toxicity

AU - Kardon, Randy H.

AU - Morrisey, Mary C.

AU - Lee, Andrew G.

N1 - Funding Information: This work was supported in part by an unrestricted grant from Research to Prevent Blindness, Inc., N.Y., N.Y. and support from the Veterans Administration through a Merit Grant and from the Rehabilitation Division (Dr. Kardon). Normative data was kindly provided by Christina Gerth, M.D., Ophthal-Hosp for Sick Children, University of Toronto, Toronto, ON. Copyright: Copyright 2008 Elsevier B.V., All rights reserved.

PY - 2006/10

Y1 - 2006/10

N2 - Objective: To report the abnormal multifocal electroretinogram (mfERG) findings in two cases of presumed ethambutol toxicity. Design: Retrospective observational case series. Participants: Two patients with ethambutol toxicity and visual loss. Testing: Multifocal electroretinography. Main outcome measure: Waveform measurements on multifocal electroretinography. Results: Two patients with bilateral visual loss due to ethambutol toxicity underwent mfERG testing that disclosed both diffuse and central field loss compatible with retinal dysfunction as a contributing mechanism to the visual field loss. Conclusion: Ethambutol toxicity affects not only the optic nerve but probably other retinal elements based upon abnormal mfERG findings.

AB - Objective: To report the abnormal multifocal electroretinogram (mfERG) findings in two cases of presumed ethambutol toxicity. Design: Retrospective observational case series. Participants: Two patients with ethambutol toxicity and visual loss. Testing: Multifocal electroretinography. Main outcome measure: Waveform measurements on multifocal electroretinography. Results: Two patients with bilateral visual loss due to ethambutol toxicity underwent mfERG testing that disclosed both diffuse and central field loss compatible with retinal dysfunction as a contributing mechanism to the visual field loss. Conclusion: Ethambutol toxicity affects not only the optic nerve but probably other retinal elements based upon abnormal mfERG findings.

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Abnormal multifocal electroretinogram (mfERG) in ethambutol toxicity

Abstract

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