A substrate-based difluoro ketone selectively inhibits Alzheimer's γ-secretase activity

Michael S. Wolfe; Martin Citron; Thekla S. Diehl; Weiming Xia; Isaac O. Donkor; Dennis J. Selkoe

doi:10.1021/jm970621b

A substrate-based difluoro ketone selectively inhibits Alzheimer's γ-secretase activity

Michael S. Wolfe, Martin Citron, Thekla S. Diehl, Weiming Xia, Isaac O. Donkor, Dennis J. Selkoe

Houston Methodist

Research output: Contribution to journal › Article › peer-review

223 Scopus citations

Original language	English (US)
Pages (from-to)	6-9
Number of pages	4
Journal	Journal of Medicinal Chemistry
Volume	41
Issue number	1
DOIs	https://doi.org/10.1021/jm970621b
State	Published - 1998

ASJC Scopus subject areas

Molecular Medicine
Drug Discovery

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10.1021/jm970621b

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title = "A substrate-based difluoro ketone selectively inhibits Alzheimer's γ-secretase activity",

author = "Wolfe, {Michael S.} and Martin Citron and Diehl, {Thekla S.} and Weiming Xia and Donkor, {Isaac O.} and Selkoe, {Dennis J.}",

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AU - Wolfe, Michael S.

AU - Citron, Martin

AU - Diehl, Thekla S.

AU - Xia, Weiming

AU - Donkor, Isaac O.

AU - Selkoe, Dennis J.

PY - 1998

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JO - Journal of Medicinal Chemistry

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A substrate-based difluoro ketone selectively inhibits Alzheimer's γ-secretase activity

ASJC Scopus subject areas

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