A simultaneous dual-isotope acquisition and imaging fusion protocol in nuclear medicine: 111In-Octreotide SPECT and 99mTC-HMDP bone SPECT

P. Zanotti-Fregonara; I. Keller; J. Y. Devaux; A. Massaro; Domenico Rubello; E. Hindé

A simultaneous dual-isotope acquisition and imaging fusion protocol in nuclear medicine: ¹¹¹In-Octreotide SPECT and ^99mTC-HMDP bone SPECT

P. Zanotti-Fregonara, I. Keller, J. Y. Devaux, A. Massaro, Domenico Rubello, E. Hindé

Research output: Contribution to journal › Article › peer-review

Abstract

In the present preliminary study, we developed a protocol for the acquisition and fusion of dual isotope tomographic (SPECT) images (¹¹¹In-Octreotide SPECT and ^99mTc-HMDP SPECT). This procedure was performed in ten consecutive patients, and the first results were encouraging: it proved to be a simple and accurate method to improve the anatomic localization of ¹¹¹In-Octreotide SPECT positive foci for the staging and follow-up of tumours expressing somatostatin receptors (Octreotide is an analog of somatostatin), particularly in discriminating bone metastases from soft tissue metastases located near to bone itself.

Original language	English (US)
Pages (from-to)	133-135
Number of pages	3
Journal	Minerva Biotecnologica
Volume	20
Issue number	3
State	Published - Sep 2008

Keywords

Bone neoplasms, secondary
Emission-computed, single-photon
In-octreotide
Isotope
Neoplasm metastasis
Tomography

ASJC Scopus subject areas

Biotechnology
Bioengineering
Applied Microbiology and Biotechnology

Cite this

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title = "A simultaneous dual-isotope acquisition and imaging fusion protocol in nuclear medicine: 111In-Octreotide SPECT and 99mTC-HMDP bone SPECT",

abstract = "In the present preliminary study, we developed a protocol for the acquisition and fusion of dual isotope tomographic (SPECT) images (111In-Octreotide SPECT and 99mTc-HMDP SPECT). This procedure was performed in ten consecutive patients, and the first results were encouraging: it proved to be a simple and accurate method to improve the anatomic localization of 111In-Octreotide SPECT positive foci for the staging and follow-up of tumours expressing somatostatin receptors (Octreotide is an analog of somatostatin), particularly in discriminating bone metastases from soft tissue metastases located near to bone itself.",

keywords = "Bone neoplasms, secondary, Emission-computed, single-photon, In-octreotide, Isotope, Neoplasm metastasis, Tomography",

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T1 - A simultaneous dual-isotope acquisition and imaging fusion protocol in nuclear medicine

T2 - 111In-Octreotide SPECT and 99mTC-HMDP bone SPECT

AU - Zanotti-Fregonara, P.

AU - Keller, I.

AU - Devaux, J. Y.

AU - Massaro, A.

AU - Rubello, Domenico

AU - Hindé, E.

PY - 2008/9

Y1 - 2008/9

N2 - In the present preliminary study, we developed a protocol for the acquisition and fusion of dual isotope tomographic (SPECT) images (111In-Octreotide SPECT and 99mTc-HMDP SPECT). This procedure was performed in ten consecutive patients, and the first results were encouraging: it proved to be a simple and accurate method to improve the anatomic localization of 111In-Octreotide SPECT positive foci for the staging and follow-up of tumours expressing somatostatin receptors (Octreotide is an analog of somatostatin), particularly in discriminating bone metastases from soft tissue metastases located near to bone itself.

AB - In the present preliminary study, we developed a protocol for the acquisition and fusion of dual isotope tomographic (SPECT) images (111In-Octreotide SPECT and 99mTc-HMDP SPECT). This procedure was performed in ten consecutive patients, and the first results were encouraging: it proved to be a simple and accurate method to improve the anatomic localization of 111In-Octreotide SPECT positive foci for the staging and follow-up of tumours expressing somatostatin receptors (Octreotide is an analog of somatostatin), particularly in discriminating bone metastases from soft tissue metastases located near to bone itself.

KW - Bone neoplasms, secondary

KW - Emission-computed, single-photon

KW - In-octreotide

KW - Isotope

KW - Neoplasm metastasis

KW - Tomography

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JO - Minerva Biotecnologica

JF - Minerva Biotecnologica

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A simultaneous dual-isotope acquisition and imaging fusion protocol in nuclear medicine: ¹¹¹In-Octreotide SPECT and ^99mTC-HMDP bone SPECT

Abstract

Keywords

ASJC Scopus subject areas

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