A Report of Cutaneous Tuberculosis in Siblings

Janna Nunez-Gussman, Jeffrey Starke, Armando Correa, Edward A. Graviss, Xi Pan, Edwina Popek, Denise W. Metry

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10 Scopus citations


Cutaneous tuberculosis is rarely seen in the United States, and we are unaware of any reports of siblings sharing the diagnosis. We report an instance of cutaneous tuberculosis affecting two sisters. The first sibling had skin biopsy specimen findings suggestive of an infectious source, but special stains and cultures were negative. Only with further evaluation using polymerase chain reaction (PCR) was the diagnosis established. The second sibling had positive staining for acid-fast bacilli, though her cultures were also negative. A high level of suspicion for tuberculosis should be maintained in otherwise healthy children with nonspecific, granulomatous disorders of the skin. PCR may be a useful tool for selected cases in which a high level of clinical suspicion exists, but special stains and cultures are negative.

Original languageEnglish (US)
Pages (from-to)404-407
Number of pages4
JournalPediatric Dermatology
Issue number5
StatePublished - Sep 1 2003

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Dermatology


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