A prospective survey of radiological bone and joint changes in primary biliary cirrhosis

P. R. Mills; R. Vallance; G. Birnie; E. M M Quigley; A. N H Main; R. J. Morgan; R. I. Russell; G. Watkinson

doi:10.1016/S0009-9260(81)80045-1

A prospective survey of radiological bone and joint changes in primary biliary cirrhosis

P. R. Mills, R. Vallance, G. Birnie, E. M M Quigley, A. N H Main, R. J. Morgan, R. I. Russell, G. Watkinson

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18 Scopus citations

Abstract

A prospective survey of radiological bone and joint changes was undertaken in 42 patients with primary biliary cirrhosis (PBC) and 23 patients with alcoholic or cyptogenic cirrhosis who formed a control population. PBC patients were commonly found to have hypertrophic osteoarthropathy (38%), joint erosions (31%) and osteoporosis, these results being significantly different from the control group. Hypertrophic osteoarthropathy most frequently affected the first metacarpal and was rarely associated with finger clubbing or clinical symptoms. Joint erosions were most evident in the hands, often associated with a positive rheumatoid factor but only accompanied by symptomatic arthritis in four cases. Patients with PBC show a high prevalence of symptomless bone and joint changes which may become manifest clinically only as the disease progresses; radiography of the hands is recommended as a screening test for these changes.

Original language	English (US)
Pages (from-to)	297-302
Number of pages	6
Journal	Clinical Radiology
Volume	32
Issue number	3
DOIs	https://doi.org/10.1016/S0009-9260(81)80045-1
State	Published - 1981

ASJC Scopus subject areas

Radiology Nuclear Medicine and imaging

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10.1016/S0009-9260(81)80045-1

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title = "A prospective survey of radiological bone and joint changes in primary biliary cirrhosis",

abstract = "A prospective survey of radiological bone and joint changes was undertaken in 42 patients with primary biliary cirrhosis (PBC) and 23 patients with alcoholic or cyptogenic cirrhosis who formed a control population. PBC patients were commonly found to have hypertrophic osteoarthropathy (38%), joint erosions (31%) and osteoporosis, these results being significantly different from the control group. Hypertrophic osteoarthropathy most frequently affected the first metacarpal and was rarely associated with finger clubbing or clinical symptoms. Joint erosions were most evident in the hands, often associated with a positive rheumatoid factor but only accompanied by symptomatic arthritis in four cases. Patients with PBC show a high prevalence of symptomless bone and joint changes which may become manifest clinically only as the disease progresses; radiography of the hands is recommended as a screening test for these changes.",

author = "Mills, {P. R.} and R. Vallance and G. Birnie and Quigley, {E. M M} and Main, {A. N H} and Morgan, {R. J.} and Russell, {R. I.} and G. Watkinson",

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T1 - A prospective survey of radiological bone and joint changes in primary biliary cirrhosis

AU - Mills, P. R.

AU - Vallance, R.

AU - Birnie, G.

AU - Quigley, E. M M

AU - Main, A. N H

AU - Morgan, R. J.

AU - Russell, R. I.

AU - Watkinson, G.

PY - 1981

Y1 - 1981

N2 - A prospective survey of radiological bone and joint changes was undertaken in 42 patients with primary biliary cirrhosis (PBC) and 23 patients with alcoholic or cyptogenic cirrhosis who formed a control population. PBC patients were commonly found to have hypertrophic osteoarthropathy (38%), joint erosions (31%) and osteoporosis, these results being significantly different from the control group. Hypertrophic osteoarthropathy most frequently affected the first metacarpal and was rarely associated with finger clubbing or clinical symptoms. Joint erosions were most evident in the hands, often associated with a positive rheumatoid factor but only accompanied by symptomatic arthritis in four cases. Patients with PBC show a high prevalence of symptomless bone and joint changes which may become manifest clinically only as the disease progresses; radiography of the hands is recommended as a screening test for these changes.

AB - A prospective survey of radiological bone and joint changes was undertaken in 42 patients with primary biliary cirrhosis (PBC) and 23 patients with alcoholic or cyptogenic cirrhosis who formed a control population. PBC patients were commonly found to have hypertrophic osteoarthropathy (38%), joint erosions (31%) and osteoporosis, these results being significantly different from the control group. Hypertrophic osteoarthropathy most frequently affected the first metacarpal and was rarely associated with finger clubbing or clinical symptoms. Joint erosions were most evident in the hands, often associated with a positive rheumatoid factor but only accompanied by symptomatic arthritis in four cases. Patients with PBC show a high prevalence of symptomless bone and joint changes which may become manifest clinically only as the disease progresses; radiography of the hands is recommended as a screening test for these changes.

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A prospective survey of radiological bone and joint changes in primary biliary cirrhosis

Abstract

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