A proposed ethical framework for interventional cognitive neuroscience: A consideration of deep brain stimulation in impaired consciousness

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56 Scopus citations

Abstract

Advances in neuromodulation techniques offer the promise of new therapeutic interventions for patients with neuropsychiatric maladies. Several complex social, ethical and policy issues will attend developments in this area. In this paper an ethical framework for clinical research in interventional cognitive neuroscience is advanced. Deep brain stimulation in traumatic brain injury is considered as a paradigm case to examine ethical obligations in human subject research. These include balancing access to novel therapies versus protection of vulnerable study populations, rational evaluation of study design and research strategies, informed consent, and the importance of achieving societal consensus for this line of scientific inquiry.

Original languageEnglish (US)
Pages (from-to)273-278
Number of pages6
JournalNeurological Research
Volume22
Issue number3
DOIs
StatePublished - Jan 1 2000

Keywords

  • Clinical pragmatism
  • Minimally conscious state
  • Neuromodulation
  • Neuropsychiatric research ethics
  • Persistent vegetative state
  • Traumatic brain injury

ASJC Scopus subject areas

  • Clinical Neurology
  • Neuroscience(all)

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